Work

Management of brain stem cavernomas in setting of multiple intracranial cavernomas (a retrospective analysis of single institutional experience).

Year: 2024

Type: article

Abstract: BACKGROUND Cavernomas in the brain stem are associated with higher hemorrhagic rates. Several studies pressed on the surgical techniques, safety and outcome results of brain stem cavernomas. In this study, we tried to find the effect of multiple cerebral cavernomas on management of brain stem cavernomas. OBJECTIVESTo describe our institutional experience in managing the brain stem cavernomas in setting of multiple cerebral cavernomas.METHODSUsing retrospective analysis for the patients who have brain stem cavernomas , older than 18 years old and at least 2 years follow up , we divided them into two groups: The (non- concomitant) group (brain stem cavernomas only) and the (concomitant) group (brainstem and non-brain stem cavernomas). . Comparative study was conducted using the demographic criteria, clinical and radiological data, management strategy, cavernomas bleeding difference rates between two groups and its effect on outcomeRESULTS Patients were divided into two groups: concomitant group (n= 21) (48.8%)) and non-concomitant group (n= 22) (51.2%)). Radiological types according to modified zabramski classification, the hemorrhagic types are IA, IB, II which accounts for 6 (27.3%) in non-concomitant group, and 15 (71.4%) in concomitant group. (χ2= 8.384, p value 0.004). Outcome using Modified Rankin Scale showed no difference between two group’s outcome neither on presentation nor after a minimum of 2 years (u=199.500, p= 0.397) and (u=180.500, p=0.145 respectively).CONCLUSION We concluded that the Multiplicity of cerebral cavernomas carries a statistically significant risk for hemorrhagic presentation in brain stem cavernoms.

Source: Pan Arab Journal of Neurosurgery/Pan arab journal of neurosurgery

DOI: 10.21608/pajn.2024.300038.1135