CHOLINE CHLORIDE DERIVATIVE-BASED NATURAL DEEP EUTECTIC SOLVENT AS NOVEL GREEN SOLVENT TO EXTRACT COMPONENTS FROM Spilanthes acmella STEM
Year: 2025
Type: article
Abstract: Conventional organic solvents, commonly used for extracting natural compounds, are toxic and pose risks to human health. To address this limitation, green solvent, using natural deep eutectic solvent (NADES), has been developed as an environmentally friendly alternative. Therefore, this study aimed to investigate the use of green solvent NADES with choline chloride and fructose as base materials for extracting active compounds from Spilanthes acmella stems. The results of extract analysis conducted through liquid chromatography-mass spectrometry (LCMS) successfully identified 17 active compounds. These compounds included citric acid, sangivamycin, (E)-ferulic acid, methylmalonic acid, lypcosamine, N-acetyl-L-glutaric acid, 6 Hydroxypiconilic acid, pivagabine, and traumatic acid. The extracted active compounds showed pharmacological effects that could be used for pharmaceutical product development.
Source: RASAYAN Journal of Chemistry
Institution: Politeknik AKA Bogor
Language: English
Subfield: Physical and Theoretical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
Funder: Academy of Finland
OpenAlex ID: W4406964296