Clinical study on the prevention of spontaneous intracerebral hemorrhage of lower extremity deep venous thrombosis by neuromuscular electrical stimulation
Year: 2020
Type: article
Study design: Clinical Trial
Abstract: Objective To investigate the effectiveness and safety of neuromuscular electrical stimulation (NMES) in the prevention of spontaneous intracranial hemorrhage (sICH) in lower extremity deep venous thrombosis (DVT). Methods A total of 76 patients with sICH from January 2019 to January 2020 were included. They were randomized to receive basic prevention methods of venous thrombosis (control group,n=38)and treatment with NMES(NMES group,n=38). The incidence of DVT of lower extremity, plasma D⁃dimer levels and adverse event rates were compared between 2 groups on 7 d of admission. The prognosis of neurological function was evaluated with Glasgow Outcome Scale (GOS) 3 months after onset. Results No pulmonary thromboembolism occurred in 2 groups within 7 d after admission, and the incidence of lower extremity DVT in the NMES group was lower than that in the control group [18.42% (7/ 38) vs. 44.74% (17/38); χ2=6.090, P=0.014]. Three days after admission, the plasma D⁃dimer level in the 2 groups was higher than that on the day of admission (P=0.000), while plasma D⁃dimer level in the NMES group was also higher than that in the control group (P=0.000). No adverse events such as skin damage or inflammation occurred in the NMES group. The prognosis of the NMES group was better than that of the control group 3 months after onset [GOS grade (3.42±1.28) vs. (2.55±1.13); t=3.124, P=0.000]. Conclusions NMES can help to prevent DVT of lower extremity in patients with sICH. DOI：10.3969/j.issn.1672⁃6731.2020.08.009
Authors: Xiao⁃qi NIE, Yu⁃hong GUO, Gang CHENG, Lu JIA
Language: English
Subfield: Internal Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4407119142