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Sodium-glucose cotransporter 2 inhibitor empagliflozin enhances autophagy and reverses remodeling in hearts with large, old myocardial infarctions

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Year: 2025
Type: article
Source: European Journal of Pharmacology
DOI: 10.1016/j.ejphar.2025.177355
Authors: Susumu Endo, Hiromitsu Kanamori, Akihiro Yoshida, Genki Naruse, Shingo Komura, Shingo Minatoguchi, Takatomo Watanabe, Tomonori Kawaguchi, Yoshihisa Yamada, Atsushi Mikami, Tatsuhiko Miyazaki, Haruhiko Akiyama, Hiroyuki Okura
Institutions: Gifu University, Asahi University Hospital, Gifu University Hospital, Center for One Medicine Innovative Translational Research
Language: English

Topic: Cardiac Fibrosis and Remodeling
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funder: Japan Society for the Promotion of Science
Awards: Significance of Autophagy in Left Ventricular Reverse Remodeling, 心筋オートファジーに着目したHFpEFの病態解明と治療応用の探索, Comprehensive genetic analysis of collagen disease therapeutic model using recombinant-inbred mice
OpenAlex ID: W4407204902
FWCI: 8.045
Cites: 53
Cited by: 13
Related to: 10
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