Work

Marine-derived bioactive molecules as modulators of immune pathways: A molecular insight into pharmacological potential

Year: 2025

Type: article

Abstract: Background: Marine ecosystems are a vast reservoir of bioactive compounds with immense pharmacological potential. Objectives: This review explores the molecular mechanisms of action, potential therapeutic applications, and challenges in the clinical translation of marine-derived bioactive molecules targeting immune pathways. Methods: A comprehensive literature review was conducted, analyzing studies on the immunomodulatory effects of marine-derived polysaccharides, peptides, and secondary metabolites. Result: In recent years, molecules derived from marine organisms, such as polysaccharides, peptides, and secondary metabolites, have shown promise as modulators of immune responses. These compounds interact with molecular pathways to enhance or suppress immune functions, making them valuable for treating diseases ranging from infections to autoimmune disorders and cancer. Conclusion: Marine-derived bioactive compounds exhibit significant potential as immunomodulatory agents by targeting various immune pathways. However, further research is required to optimize their pharmacological applications and address challenges in clinical translation.

Source: Pharmacia

DOI: 10.3897/pharmacia.72.e141923