Plant-derived nanovesicles and therapeutic application
Year: 2025
Type: review
Abstract: Plant-derived nanovesicles (PDNVs) are becoming more popular as promising therapeutic tools owing to their diversity, cost-effectiveness, and biocompatibility with very low toxicity. Therefore, this review aims to discuss the methods for isolating and characterizing PDNVs and emphasize their versatile roles in direct therapeutic applications and drug delivery systems. Their ability to effectively encapsulate and deliver large nucleic acids, proteins, and small-molecule drugs was highlighted. Moreover, advanced engineering strategies, such as surface modification and fusion with other vesicles, have been developed to enhance the therapeutic effects of PDNVs. Additionally, we describe key challenges related to this field, encouraging further research to optimize PDNVs for various clinical applications for prevention and therapeutic purposes. The distinctive properties and diverse applications of PDNVs could play a crucial role in the future of personalized medicine, fostering the development of innovative therapeutic strategies.
Source: Pharmacology & Therapeutics
Authors: Dokyung Jung, Na-Eun Kim, Sua Kim, Ju-Hyun Bae, Il-Young Jung, Kyung-Won Doh, Byungheon Lee, Do-Kyun Kim, Young-Eun Cho, Moon-Chang Baek
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $5,660
Awards: G1986540668, G5607409405
OpenAlex ID: W4408019339