Work

Supplementary Figure 4 from A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC

Year: 2025

Type: supplementary-materials

Abstract: Combination therapy with INK128 and palbociclib is effective against HNSCC xenograft

DOI: 10.1158/2767-9764.28688364

Authors: Yusuke Goto, Keiichi Koshizuka, Toshinori Ando, Hiroki Izumi, Xingyu Wu, Kuniaki Sato, Tomohiko Ishikawa, Kyle Ford, Xiaodong Feng, Zhiyong Wang, Nadia Arang, Michael M. Allevato, Ayush Kishore, Prashant Mali, J. Silvio Gutkind

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4408934039

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