Year: 2025
Type: article
Abstract: Cancer is a highly prevalent disease associated with high mortality.As part of its treatment, a significant percentage of patients will require surgery, some of them with a high probability of major bleeding.To reduce the impact of surgical bleeding, patient blood management (PBM) programs have been developed and implemented, which include intraoperative blood-saving strategies, including the collection of blood from the surgical field for processing and re-infusion, also known as intraoperative autologous transfusion or intraoperative cell salvage (ICS).In relation to its use in oncologic surgery, there have been historical considerations related to the concern of collecting tumor cells, which, if re-infused together with red blood cells, could eventually participate in the generation of metastasis and tumor recurrence.Different accumulated evidence would indicate that the risk of this occurrence would be low or non-existent and that its potential occurrence would be compensated through the benefits obtained with the use of the ICS technique in an indirect manner.Thus, some medical societies have made recommendations on its use in this specific subgroup of patients.This paper will review generalities about the technique, analyzing its advantages and disadvantages.The process of metastasis formation will be described and how different stages of the perioperative period, including ICS, could affect this process.We will also review the experimental evidence accumulated in relation to the use of ICS in oncologic surgery and finally we will end with a summary of the main recommendations regarding its use published to date.
Source: Revista Chilena de Anestesia
Language: Spanish
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409015698