Work

Proof of concept study for developing 1-thienyl-β-carboline derivatives as IDO1 and TDO dual inhibitors to treat Parkinson's disease complicating depression

Year: 2025

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2025.117597

Authors: Xuan Chen, Mengxiao Zhu, Qingyuan Shi, Zhenquan Huang, Junjie Zhu, Pingping Sun, Hongzhen Zhang, Lili Yang, Xun Chen, Yu Zhang, Lili Feng, Katsuhisa Horimoto, Fei Li, Feng Han, Dongyin Chen

Institutions: Jiangsu Food and Pharmaceutical Science College, Nanjing Medical University

Language: English

Topic: Synthesis and bioactivity of alkaloids

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Foundation for Innovative Research Groups of the National Natural Science Foundation of China

Awards: G1455814869, G2149516758

OpenAlex ID: W4409224992

FWCI: 2.229

Cites: 26

Cited by: 8

Related to: 10