Clinical Efficacy of Zarūr-i-Kath (Pharmacopoeial Preparation) in Case of Qulāʻ (Stomatitis) – An Open-label Clinical Trial
Year: 2022
Type: article
Study design: Clinical Trial
Abstract: Background and Objective: The study aims to validate the pharmacopoeial formulation Zarūr-i-Kath for its efficacy and safety profile in the treatment of Qulāʻ (recurrent aphthous stomatitis). Methodology: An open-label clinical trial was conducted on 92 patients with Qulāʻ , adhering to Good Clinical Practice guidelines. Zarūr-i-Kath was applied locally twice daily for 7 days. Clinical assessment was performed on the 3 rd and 7 th days of treatment. Results: The overall clinical response was 89.14%, with 36.95% of patients achieving complete relief, 27.17% showing significant relief, 25% showing partial relief, and 10.86% not responding to the treatment. No adverse effects were reported, and laboratory investigations remained within normal limits throughout the study. Conclusion: The clinical validation of Zarūr-i-Kath in the treatment of Qulāʻ demonstrates its efficacy and safety, supporting the traditional claims of Unani physicians. Future studies should focus on improving the formulation’s ease of use, potentially as a lotion or gel, to increase its clinical acceptability.
Authors: Athar Parvez Ansari, N. Zaheer Ahmad, Noman Anwar, K. Kabiruddin Ahmad, Abdul Raheem, Asim Ali Khan
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4409306320