Work

Histoplasma Endocarditis of the Native Mitral Valve in a Patient With End-Stage Renal Disease: A Diagnostic Challenge

Year: 2025

Type: article

Abstract: Histoplasma is a rare cause of endocarditis. It usually occurs in immunosuppressed patients, but diagnosis can be challenging given its nonspecific clinical and laboratory findings. This report describes the case of a patient with end-stage renal disease and multiple hospitalizations who was diagnosed with blood culture-negative infective endocarditis and subsequently found to have Histoplasma endocarditis of his native mitral valve. Our patient’s nonspecific symptoms posed a diagnostic challenge, which resulted in delayed diagnosis and treatment.

Source: Cureus

DOI: 10.7759/cureus.82246

Authors: Patrick Berchie, Moatamn Skuk, Samuel Dadzie, Baffour Otchere, Zola Nlandu

Institutions: Piedmont Athens Regional, University of Georgia, Augusta University

Language: English

Topic: Infective Endocarditis Diagnosis and Management

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409429096