Mechanochemical Sequential Deoxygenative Cross-Coupling Reactions of Phenols Under Ruthenium-Nickel Catalysis
Year: 2025
Type: article
Abstract: Herein, we report the first mechanochemical strategy for the Ru-catalyzed deoxygenative borylation of free phenols via C-O bond cleavage. This Ru-catalyzed phenolic borylation approach has been successfully extended to the Suzuki-Miyaura-type cross-coupling of phenols with aryl bromides. The protocol accepts a wide scope of phenolic substrates, allowing the synthesis of aryl pinacolboranes and biphenyl structures in excellent yields and serving as a better alternative to classical cross-coupling reactions in the context of pot, atom, and step economy synthesis.
Source: Molecules
Institutions: Matej Bel University, Charotar University of Science and Technology, Czech Academy of Sciences, Czech Academy of Sciences, Institute of Inorganic Chemistry, Sardar Patel University, Osnabrück University, Interregional Academy of Personnel Management, Banaras Hindu University, Comenius University Bratislava, Gulf University for Science & Technology, Georgian American University, Chitkara University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,258
OpenAlex ID: W4409606007