Atypical Presentations of Hypopituitarism: A Report of Two Cases
Year: 2025
Type: article
Study design: Case Report
Abstract: Hypopituitarism is a relatively uncommon endocrine disorder with varying prevalence rates among different populations. Growth hormone deficiency is one of the common hormone deficiencies in hypopituitarism, followed by deficiencies in gonadotropins, thyroid-stimulating hormone, adrenocorticotropic hormone, and prolactin levels. Most symptoms are nonspecific, so diagnosis may be delayed. We present here two cases of hypopituitarism in elderly males with atypical clinical presentations. The first case involves a 76-year-old gentleman presenting with hypoglycemia, hyponatremia, and hypotension, and the second case describes a 58-year-old gentleman presenting with generalized weakness, hypoglycemia, hypotension, drowsiness, and confusion, which upon investigation was diagnosed to have hypopituitarism. These cases highlight the importance of considering hypopituitarism in the differential diagnosis of patients presenting with recurrent hypoglycemia, hyponatremia, and hypotension.
Authors: Deepak Kumar, Jaynul Aabidin, Divendu Bhushan, Sunil Kumar
Institution: All India Institute of Medical Sciences, Patna
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410032081