Get started
Work

Development and validation of the epilepsy scale among the system of quality of life instruments for chronic diseases QLICD-EP (V2.0):A multicenter longitudinal study

Year: 2025
Type: article
Abstract: OBJECTIVES: To develop and evaluate the epilepsy scale among the System of Quality of Life Instruments for Chronic Diseases QLICD-EP(V2.0). METHODS: The QLICD-EP(V2.0) was developed based on a modular approach and programmed decision procedures with multiple nominal and focus group discussions. The data measuring quality of life (QOL) three times before and after treatment of patients with epilepsy (PWE) was used to evaluate the psychometric properties of the scale, including reliability, validity, and responsiveness. RESULTS: The Cronbach's α coefficient of the total scale was 0.902. The test-retest reliability of the total scale was 0.913, and the ICC(95 %CI) of the total scale was 0.953(0.928,0.969). Correlation and confirmatory factor analyses by the structural equation model confirmed good construct validity. Correlation analysis showed good criterion-related validity when using the Short Form-36 Health Survey (SF-36) as a criterion. The paired t-test results showed that the special mentality facet was statistically significant (P < 0.05) before and after the treatment with standard response mean (SRM) being 0.31, there was no statistical significance in other domains and facets with SRM being less than 0.50, which was a low effect. CONCLUSION: QLICD-EP (V2.0) can be used to clinically assess the QOL of PWE in China. Providing a scientific basis for precision medicine and contributing to global health.
DOI: 10.1016/j.yebeh.2025.110444
Authors: Yujie Zhou, Wenhua Chi, Mengke Ding, Haifeng Ding, Chuanzhi Xu, Chonghua Wan
Language: English
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $3,060
OpenAlex ID: W4410051794
FWCI: 0.498
Cites: 36
Cited by: 1
Related to: 10