Work

Advancing breast cancer therapy in the era of molecular diagnostics

Year: 2025

Type: review

Abstract: Advances in cancer biology and drug development now enable treatments tailored to individual tumor profile. Targeting specific molecular alterations marked a significant step forward in cancer care, including breast cancer. Access to these therapies is improving thanks to the implementation of molecular tumor boards and efforts to provide molecular diagnostics at sustainable costs for all. In this context, we highlight recent progress in breast cancer therapy, focusing on biomarker-driven approaches, immunotherapy, and precision medicine paving the way for increasingly personalized and effective options.

Source: The Breast

DOI: 10.1016/j.breast.2025.104488

Authors: Maria Grazia Carnevale, Riccardo Ray Colciago, Maria Carmen De Santis, Laura Cortesi, Cinzia De Marco, Antonio Marra, Andrea Vingiani, Franco Nolè, Giuseppe Curigliano, Giancarlo Pruneri, Antonio Llombart-Cussac, Serena Di Cosimo, Javier Cortes

Institutions: Fondazione IRCCS Istituto Nazionale dei Tumori, University of Milano-Bicocca, Azienda Sanitaria Unità Locale di Reggio Emilia, European Institute of Oncology, University of Milan, Hospital Arnau de Vilanova, IDCQ Hospitales y Sanidad, S.L.U., Universidad Europea de Madrid

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,200

Funders: Associazione Italiana di Oncologia Medica, European Commission

Award: G690532135

OpenAlex ID: W4410246400

FWCI: 1.125

Cites: 98

Cited by: 11

Related to: 10