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Diagnosis and Management of Cardiac Amyloidosis: The Role of Multimodal Imaging—A Mini Review

Year: 2025
Type: article
Abstract: Cardiac amyloidosis is a disease characterized by the deposition of misfolded proteins in the myocardium, leading to restrictive cardiomyopathy. It comprises two subtypes: immunoglobulin light chain cardiac amyloidosis (AL) and transthyretin cardiac amyloidosis (ATTR). ATTR is classified as wild-type (wtATTR) and hereditary (hATTR), depending on the presence or absence of a transthyretin (TTR) genetic mutation. The diagnosis of cardiac amyloidosis is challenging due to nonspecific symptoms with other cardiac conditions, often resulting in misdiagnosis. This mini review provides an in-depth analysis of cardiac amyloidosis, focusing on its subtypes, clinical manifestations, diagnostic multimodal imaging, and recent therapeutic advancements.
DOI: 10.4236/wjcd.2025.155021
Authors: Camila Ponce-Acosta, Maria Jose Santa-Ana-Bayona, Gilberto H. Acosta-Gutiérrez, Pavel Martinez-Dominguez, Santiago Luna-Alcala, Alfonso Gonzalez-Trejo, Hugo A. Valencia-Hernandez, Enrique C. Guerra, Nilda Espinola-Zavaleta
Institutions: Universidad La Salle, Universidad Autónoma de Ciudad Juárez, Autonomous University of Chihuahua, Universidad Nacional Autónoma de México, Universidad Villa Rica, Centro Médico ABC, Instituto Nacional de Cardiología
Language: English
Open Access status: diamond
OpenAlex ID: W4410696507
FWCI:
Cites: 45
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Related to: 10