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Enterococcus faecalis Metabolizes Matairesinol to Enterolactone, Which Promotes E. faecalis Growth and Glut4-Dependent Glucose Uptake in Adipocytes

Year: 2025
Type: article
Abstract: Objectives: 1) Assess the impact of matairesinol (MA) and enterolactone (ENL) on Enterococcus faecalis proliferation; 2) Determine whether E. faecalis metabolizes MA to ENL; 3) Evaluate the effects of MA and ENL on glucose uptake in 3T3-L1 differentiated adipocytes; 4) Investigate the underlying mechanisms driving these effects.
DOI: 10.1016/j.cdnut.2025.106414
Authors: Emily Bayliss, Merritt Smith, Rochelle Miller, Josiah Chung, Heidi Bosch, Olivia Mankos, Seth Woodfin, Megan Bones, Matthew H Becker, Vhuthu Madzinge, William Moore
Language: English
Open Access status: gold
Estimated APC paid: $5,000
OpenAlex ID: W4410839811
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