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Optimization of 1-Methyl-3-(pyridin-3-yl)-1H-indol Derivatives as ROR1 Inhibitors with Improved Activity and Selectivity

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Year: 2025
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c00189
Authors: Qingquan Zheng, Xingyang Qiu, Dongdong Luo, Hulin Ma, Yue Ming, Wenchen Pu, Min Ai, Jianhua He, Yong Peng
Institutions: West China Hospital of Sichuan University, State Key Laboratory of Biotherapy
Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: China Postdoctoral Science Foundation, West China Hospital, Sichuan University
Awards: G2136406795, G219059348, G2855491278, G799006812
OpenAlex ID: W4410944831
FWCI: 2.637
Cites: 44
Cited by: 10
Related to: 10
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