Effect of a distal attachment cuff on adenoma detection rate in screening colonoscopy: Randomized controlled trial in the Spanish population
Year: 2025
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Endocuff Vision (EV) is a disposable device designed to improve polyp detection. The primary aim of this study was to evaluate the effect of EV on adenoma detection rate (ADR) and mean number of adenomas per patient (MAP). This multicenter randomized controlled trial compared EV-assisted colonoscopy (EAC) and standard colonoscopy (SC). Patients were referred due to a positive fecal immunochemical test (FIT) in a bowel cancer screening program (BCSP), direct screening colonoscopy without prior FIT, surveillance colonoscopy, or family history of colorectal cancer. In total, 1437 patients (55.9% male; median age, 59 years) were randomized at eight Spanish university hospitals. No significant differences were found in either the ADR (EAC vs. SC, 55.8% vs. 54.3%; P = 0.576) or the MAP (1.60 vs. 1.35; P = 0.03). Compared with SC, EAC was not associated with a significant improvement in detection rates for advanced adenomas, sessile serrated lesions, or advanced sessile serrated lesions. There was no difference in cecal intubation rate but the successful ileal intubation rate, among patients in whom it was attempted, was lower with EAC (64.3% vs. 86.5% with SC; P = 0.001). EV did not improve either ADR or MAP. EV may increase difficulty of ileal intubation whenever it is attempted.
Source: Endoscopy International Open
DOI: 10.1055/a-2625-5985
Authors: Aurora Burgos García, Alberto Herreros de Tejada, Carlos Ferre Aracil, Oscar Nogales, Sofía Parejo, Mariana Tavecchia, Belen Agudo, Héctor Julián Canaval Zuleta, Angel Cañete Ruiz, Diego De Frutos Rosa, Julia Arribas Anta, Beatriz Peñas, Rodrigo Borobia, Juan L Mendoza, Cristina Bernardo, Pedro De María, Natalia Lopez Palacios, Mirella Jiménez Gómez, Guillermo Cacho Acosta, Marta Cuadros Martínez, Patricia Mayor Delgado, María Ángeles Ruiz Ramírez, Ana Royuela Vicente, Enrique Rodriguez de Santiago, Consuelo Froilán
Institutions: Hospital Universitario La Paz, Hospital La Paz Institute for Health Research, Centro de Investigación Biomédica en Red de Cáncer, Hospital Universitario Puerta de Hierro Majadahonda, Hospital General Universitario Gregorio Marañón, Instituto Ramón y Cajal de Investigación Sanitaria, Hospital Universitario Ramón y Cajal, Hospital Universitario Fundación Alcorcón, Hospital Universitario 12 De Octubre, Hospital Clínico San Carlos, Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,825
Funder: Norgine
OpenAlex ID: W4410946366