Work

Experiment and modeling of concentration-dependent diffusion in a solution with dual transport-phase flow for paper-based sensing

Year: 2025

Type: article

Abstract: solutions - such solutes which have weak bonds with water (solvent) can have decoupled transport-phases: (i) water flow, followed by (ii) analyte diffusion. We have presented a video processing algorithm to automatically extract the time-series analyte and water flow distance measurements by analyzing the pixel values frame-by-frame of the recorded experiment videos. This ensures consistency in distance measurements among the experiments. We finally explain the physical process of the flow using a corresponding mathematical model to describe the concentration effects in paper-like materials. The model includes how analyte undergoes drift force (due to water flow velocity) along with diffusion. We found that the numerical solution of the model agrees with the trends seen in the experimental results. This can help us better understand the liquid-wicking behavior in different concentrations through a mathematical model and provide guidance in the design and optimization of paper-based sensors.

Source: RSC Advances

DOI: 10.1039/d5ra02347e

Authors: Md. Saykat Hassan Sajib, Md. Sakif Rafid, M. Ryyan Khan

Institution: East West University

Language: English

Topic: Biosensors and Analytical Detection

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,042

Funder: Purdue University