Work

Novel delivery strategy: finasteride-loaded solid lipid nanoparticles for improved androgenetic alopecia therapy

Year: 2025

Type: article

Abstract: H-NMR spectra could be due to the protons attached, which have substantial exchangeability and result in a probable disappearance in the NMR spectra. The investigation showed the highest skin retention of 226.76 μg of FINA by NP7, along with a modest amount of FINA permeated (71.23 μg) during the study period of 18 h. The animal model using C57BL/6 mice showed a notable enhancement in hair covering and growth in Group IV, which received treatment without any visible cutaneous reaction on the skin. This outcome underscores the effectiveness and importance of the formulation developed using a suitable combination of LPC and NTC, which could be used to manage AGA effectively.

Source: RSC Advances

DOI: 10.1039/d5ra00399g

Authors: Harekrishna Roy, Balaji Maddiboyina, Bhabani Shankar Nayak, Raghvendra A. Bohara

Institutions: KIIT University, D.Y. Patil Education Society

Language: English

Topic: Advancements in Transdermal Drug Delivery

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042