Work

Unveiling The Metabolic-Neurophysiological Interplay of Vitamin B₁₂ In Young Adults: A Systematic Review

Year: 2025

Type: review

Abstract: Vitamin B12 (cobalamin) is a vital micronutrient involved in DNA synthesis, red blood cell formation, and neurological function. Its deficiency, increasingly common among young adult females—particularly those adhering to vegetarian or vegan diets—can result in biochemical imbalances, disrupted nerve function, and cognitive impairments. This review consolidates current findings on the physiological implications of Vitamin B12 deficiency in this demographic. We explore biochemical markers such as homocysteine and methylmalonic acid, the impact on nerve conduction and electrophysiology, and associated neurocognitive deficits. We also assess diagnostic strategies and intervention approaches. With the prevalence of plant-based diets rising, this work underscores the need for targeted screening and early correction strategies to mitigate long-term neurological and systemic consequences.

Source: Journal of Neonatal Surgery

DOI: 10.63682/jns.v14i8.7139

Authors: Deepanshi Sharma, Amandeep Singh, Nisha Phakey, Yash Prashar

Institutions: Chitkara University, O. P. Jindal Global University

Language: English

Topic: Folate and B Vitamins Research

Subfield: Nutrition and Dietetics

Field: Nursing

Domain: Health Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: diamond

Funder: Chitkara University