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Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025

Year: 2025
Type: article
Abstract: Chikungunya virus re-emerged on Réunion Island in August 2024, 18 years after a first major outbreak. Analysis of 173 genomes from the current epidemic reveals a monophyletic clade with mutations linked to adaptation to Aedes albopictus mosquitoes, including E1-A226V. Bayesian inference suggests only brief cryptic circulation before detection. The same lineage was also detected on Mayotte Island in March 2025. Continued spread and confirmed travel-related cases in mainland France and globally highlight the risk of wider regional and international dissemination.
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4411097501
FWCI: 35.19
Cites: 12
Cited by: 49
Related to: 10