Work

Construction of the reduced nicotinamide adenine dinucleotide salvage pathway in artificial cells and its application in amino acid synthesis

Year: 2025

Type: article

Abstract: and α-ketoglutarate to glutamate by introducing additional glutamate dehydrogenase (GDH) inside artificial cells. The successful reconstitution of the NADH synthesis pathway lays the foundation for fabricating artificial cells with complicated metabolic networks.

Source: Chemical Science

DOI: 10.1039/d5sc00852b

Authors: Yiming Liu, Shanshan Du, Xiangxiang Zhang, Chao Li, Shubin Li, Wenxia Xu, Jingjing Zhao, Wei Mu, Xiaojun Han

Institution: Harbin Institute of Technology

Language: English

Topic: Microbial Metabolic Engineering and Bioproduction

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

Funders: National Natural Science Foundation of China, China Postdoctoral Science Foundation, Natural Science Foundation of Heilongjiang Province

Awards: G3977205890, G4732753621, G615222957, G7555801091, G8843275055

OpenAlex ID: W4411101720

FWCI: 1.325

Cites: 51

Cited by: 6

Related to: 10