Testing indoor residual spraying coverage targets for malaria control, Bioko, Equatorial Guinea
Year: 2025
Type: article
Abstract: Objective: To test 50% indoor residual spraying coverage (percentage of households sprayed) for non-inferiority against the recommended 80% coverage for malaria control. Methods: infection between baseline and post-intervention using difference-in-differences analysis within a survey-weighted binomial generalized linear model. Given differences between the arms at baseline, we adjusted the model for indoor residual spraying coverage at baseline. Findings: infection was no greater in the intervention arm than in the control arm (odds ratio: 0.89; 95% CI: 0.58-1.36), with the upper CI being lower than the non-inferiority margin of 1.43. Conclusion: There was no evidence that 50% coverage was inferior in preventing malaria, which supports the use of this target in settings where this level makes indoor residual spraying feasible by increasing the cost-effectiveness and equity of the intervention.
Authors: Guillermo García, Dianna Hergott, David Galick, Olivier Tresor Donfack, Liberato Motobe Vaz, Lucas Nze Nchama, Jeremías Mba Eyono, Restituto Nguema Avue, Matilde Riloha Rivas, Marcos Iyanga, Faustino Ebang Bikie, Teresa Ondo Mfumu, Wonder Phiri, Michael von Fricken, Robert Reiner Jr, David Smith, Carlos Guerra
Language: English
Topic: Malaria Research and Control
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411299264