Work

The Effect of Visual Deprivation During Cognitive Motor Dual Task Training on Cognitive Function in Type 2 Diabetes Mellitus

Year: 2025

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: Background Diabetes Mellitus (DM) is a chronic metabolic disorder caused by hyperglycemia, impaired insulin secretion, and insulin resistance. Type 2 diabetes mellitus (T2DM) is associated with an increased risk for cognitive dysfunction. Cognitive motor dual task blindfold training (CMDBT) forces the brain to process motor tasks in one of the four procedural memory centers: the basal ganglia, cerebellum, supplementary motor area, and premotor cortex. Hence, it helps improve cognition in patients with T2DM. Methods A randomized controlled trial was conducted with 62 participants diagnosed with type 2 diabetes mellitus. Baseline cognition was assessed using the Montreal Cognitive Assessment (MoCA). The experimental group (n=31) underwent cognitive-motor dual-task blindfold training combined with aerobic and resistance exercises, while the control group (n=31) received conventional aerobic and resistance training only. Both groups participated in their respective interventions three times weekly for 12 weeks. Post-intervention cognitive function was re-assessed using the MoCA scale. Results Statistical analysis of the data revealed that there was a significant improvement in cognitive function in experimental group A subjects, with a significant mean difference observed in group A compared to group B. The P value of MoCA was 0.0001 in experimental group A subjects. Conclusion CMDBT is more effective than conventional exercise in enhancing cognitive function in individuals with T2DM and may serve as a valuable intervention to mitigate diabetes-associated cognitive decline.

Source: F1000Research

DOI: 10.12688/f1000research.162466.2