Year: 2025
Type: article
Abstract: Alstonia scholaris, also known as the "devil's tree," has attracted a lot of scientific attention because of its diverse range of medicinal uses, especially in the treatment of cancer, and its rich phytochemical composition. Recent advancements in the pharmacological characteristics, phytochemical characterization, and therapeutic potential of A. scholaris are highlighted in this review, with a focus on its anticancer potential. Numerous bioactive substances, such as terpenoids, alkaloids, flavonoids, and phenolic compounds, have shown cytotoxic activity against various cancer cell lines. According to studies, these components may prevent the growth of new blood vessels (angiogenesis), inhibit tumor cell proliferation, and encourage programmed cell death (apoptosis). This paper compiles recent in vitro, in vivo, and limited clinical studies and discusses the future scope for therapeutic application.
Authors: Vikas R. Patil Vikas R. Patil, Vikram R. Tadvi Vikram R. Tadvi, Miss. Priyanka S. Ahire Miss. Priyanka S. Ahire, Mr. Jayesh C. Chaudhar Mr. Jayesh C. Chaudhar, Dr. Rajesh A. Ahirrao Dr. Rajesh A. Ahirrao
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4411458290