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Second-Generation Onlay Patellofemoral Prostheses: 14-Year Outcomes Redefining Isolated Patellofemoral Osteoarthritis Management

Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Isolated patellofemoral osteoarthritis is a frequent source of anterior knee pain in middle-aged patients. Second-generation onlay patellofemoral prostheses were developed to address limitations of earlier designs and improve clinical outcomes. Methods: We conducted a retrospective study of 231 patients (mean age 52.2 years) who underwent patellofemoral arthroplasty with a second-generation onlay implant between 2009 and 2023. Clinical outcomes were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index and Kaplan-Meier survival analysis. Radiological evaluation included signs of loosening, progression of tibiofemoral osteoarthritis, and patellar alignment. Results: < .001). The implant survival rate was 96.6% at the final follow-up. Early clinical gains were significantly influenced by implant type, while long-term outcomes were associated with patient-specific factors such as body mass index and activity level. Radiological progression of tibiofemoral disease was observed in 6.1% of patients. Conclusions: Second-generation onlay patellofemoral prostheses yield sustained functional improvement and low complication rates when used in carefully selected patients. These findings support their use as a reliable solution for isolated patellofemoral osteoarthritis. Level of Evidence: III.
Language: English
Subfield: Surgery
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,500
OpenAlex ID: W4412459348
FWCI: 1.4
Cites: 12
Cited by: 2
Related to: 10