Polygenic prediction of body mass index and obesity through the life course and across ancestries
Year: 2025
Type: article
Study design: Observational Study
Abstract: Polygenic scores (PGSs) for body mass index (BMI) may guide early prevention and targeted treatment of obesity. Using genetic data from up to 5.1 million people (4.6% African ancestry, 14.4% American ancestry, 8.4% East Asian ancestry, 71.1% European ancestry and 1.5% South Asian ancestry) from the GIANT consortium and 23andMe, Inc., we developed ancestry-specific and multi-ancestry PGSs. The multi-ancestry score explained 17.6% of BMI variation among UK Biobank participants of European ancestry. For other populations, this ranged from 16% in East Asian-Americans to 2.2% in rural Ugandans. In the ALSPAC study, children with higher PGSs showed accelerated BMI gain from age 2.5 years to adolescence, with earlier adiposity rebound. Adding the PGS to predictors available at birth nearly doubled explained variance for BMI from age 5 onward (for example, from 11% to 21% at age 8). Up to age 5, adding the PGS to early-life BMI improved prediction of BMI at age 18 (for example, from 22% to 35% at age 5). Higher PGSs were associated with greater adult weight gain. In intensive lifestyle intervention trials, individuals with higher PGSs lost modestly more weight in the first year (0.55 kg per s.d.) but were more likely to regain it. Overall, these data show that PGSs have the potential to improve obesity prediction, particularly when implemented early in life.
Source: Nature Medicine
Authors: Roelof A. J. Smit, Kaitlin H. Wade, Qin Hui, Joshua D. Arias, Xianyong Yin, Malene R. Christiansen, Loic Yengo, Michael H. Preuss, Mariam Nakabuye, Ghislain Rocheleau, Sarah E. Graham, Victoria L. Buchanan, Geetha Chittoor, Marielisa Graff, Marta Guindo-Martínez, Yingchang Lu, Eirini Marouli, Saori Sakaue, Cassandra N. Spracklen, Sailaja Vedantam, Emma P. Wilson, Shyh-Huei Chen, Teresa Ferreira, Yingjie Ji, Tugce Karaderi, Kreete Lüll, Moara Machado, Deborah E. Malden, Carolina Medina-Gomez, Amy Moore, Sina Rüeger, Masato Akiyama, Matthew A. Allison, Marcus Alvarez, Mette K. Andersen, Vivek Appadurai, Liubov Arbeeva, Eric Bartell, Seema Bhaskar, Lawrence F. Bielak, Joshua C. Bis, Sailalitha Bollepalli, Jette Bork-Jensen, Jonathan P. Bradfield, Yuki Bradford, Caroline Brandl, Peter S. Braund, Jennifer A. Brody, Ulrich Broeckel, Kristoffer S. Burgdorf, Brian E. Cade, Qiuyin Cai, Silvia Camarda, Archie Campbell, Marisa Cañadas-Garre, Jin-Fang Chai, Alessandra Chesi, Seung Hoan Choi, Paraskevi Christofidou, Christian Couture, Gabriel Cuellar-Partida, Rebecca Danning, Frauke Degenhardt, Graciela E. Delgado, Alessandro Delitala, Ayşe Demirkan, Xuan Deng, Alexander Dietl, Maria Dimitriou, Latchezar Dimitrov, Rajkumar Dorajoo, Fabian Eichelmann, Anders U. Eliasen, Jorgen E. Engmann, Michael R. Erdos, Zammy Fairhurst-Hunter, Aliki-Eleni Farmaki, Jessica D. Faul, Juan-Carlos Fernandez-Lopez, Lukas Forer, Mirjam Frank, Sandra Freitag-Wolf, Lars G. Fritsche, Christian Fuchsberger, Tessel E. Galesloot, Yan Gao, Frank Geller, Olga Giannakopoulou, Franco Giulianini, Anette P. Gjesing, Anuj Goel, Scott D. Gordon, Mathias Gorski, Jakob Grove, Xiuqing Guo, Stefan Gustafsson, Jeffrey Haessler, Thomas F. Hansen, Aki S. Havulinna, Simon J. Haworth, Nancy Heard-Costa, Daiane Hemerich, Heather M. Highland, George Hindy, Yuk-Lam Ho, Edith Hofer, Elizabeth Holliday, Katrin Horn, Whitney E. Hornsby, Jouke-Jan Hottenga, Hongyan Huang, Jie Huang, Alicia Huerta-Chagoya, Shaofeng Huo, Mi Yeong Hwang, Chii-Min Hwu, Hiroyuki Iha, Daisuke D. Ikeda, Masato Isono, Anne U. Jackson, Iris E. Jansen, Yunxuan Jiang, Ingegerd Johansson, Anna Jonsson, Torben Jørgensen, Ioanna P. Kalafati, Masahiro Kanai, Stavroula Kanoni, Line L. Kårhus, Anuradhani Kasturiratne, Tomohiro Katsuya, Takahisa Kawaguchi, Rachel L. Kember, Katherine A. Kentistou, Daeeun Kim, Han-Na Kim, Young Jin Kim, Marcus E. Kleber, Maria J. Knol, Azra Kurbasic, Marie Lauzon, Phuong Le, Rodney Lea, Jong-Young Lee, Wen-Jane Lee, Hampton L. Leonard, Hengtong Li, Shengchao A. Li, Xiaohui Li, Xiaoyin Li, Jingjing Liang, Honghuang Lin, Kuang Lin, Jun Liu, Xueping Liu, Ken Sin Lo, Jirong Long, Laura Lores-Motta, Jian’an Luan, Valeriya Lyssenko, Leo-Pekka Lyytikäinen, Anubha Mahajan, Md Zubbair Malik, Vasiliki Mamakou, Massimo Mangino, Ani Manichaikul, Jonathan Marten, Manuel Mattheisen, Aaron F. McDaid, Quanshun Mei, Heike Meiselbach, Tori L. Melendez, Yuri Milaneschi, Jason E. Miller, Iona Y. Millwood, Pashupati P. Mishra, Ruth E. Mitchell, Line T. Møllehave, Nina Mononen, Sören Mucha, Matthias Munz, Juha Mykkänen, Masahiro Nakatochi, Giuseppe Giovanni Nardone, Christopher P. Nelson, Maria Nethander, Chu Won Nho, Aneta A. Nielsen, Ilja M. Nolte, Suraj S. Nongmaithem, Raymond Noordam, Ioanna Ntalla, Teresa Nutile, Anita Pandit, Marc Pauper, Eva R. B. Petersen, Liselotte V. Petersen, Francesco Piluso, Ozren Polašek, Alaitz Poveda, Saiju Pyarajan, Laura M. Raffield, Hiromi Rakugi, Julia Ramirez, Asif Rasheed, Dennis Raven, Nigel W. Rayner, Carlos Riveros, Rebecca Rohde, Daniela Ruggiero, Sanni E. Ruotsalainen, Kathleen A. Ryan, Maria Sabater-Lleal, Aurora Santin, Richa Saxena, Markus Scholz, Botong Shen, Jingchunzi Shi, Jae Hun Shin, Carlo Sidore, Julia Sidorenko, Xueling Sim, Roderick C. Slieker, Albert V. Smith, Jennifer A. Smith, Laura J. Smyth, Lorraine Southam, Valgerdur Steinthorsdottir, Liang Sun, Fumihiko Takeuchi, Kent D. Taylor, Bamidele O. Tayo, Catherine Tcheandjieu, Natalie Terzikhan, Paola Tesolin, Alexander Teumer, Elizabeth Theusch, Deborah J. Thompson, Gudmar Thorleifsson, Paul R. H. J. Timmers, Stella Trompet, Constance Turman, Simona Vaccargiu, Sander W. van der Laan, Peter J. van der Most, Jan B. van Klinken, Jessica van Setten, Shefali S. Verma, Niek Verweij, Yogasudha Veturi, Carol A. Wang, Chaolong Wang, Jun-Sing Wang, Lihua Wang, Ya Xing Wang, Zhe Wang, Helen R. Warren, Wen Bin Wei, Wanqing Wen, William A. Wheeler, Ananda R. Wickremasinghe, Matthias Wielscher, Bendik S. Winsvold, Andrew Wong, Matthias Wuttke, Rui Xia, Ken Yamamoto, Jingyun Yang, Jie Yao, Hannah Young, Noha A. Yousri, Lei Yu, Lingyao Zeng, Weihua Zhang, Xinyuan Zhang, Jing-Hua Zhao, Wei Zhao, Wei Zhou, Martina E. Zimmermann, Magdalena Zoledziewska, Leen M. ‘t Hart, Linda S. Adair, Hieab H. H. Adams, Carlos A. Aguilar-Salinas, Fahd Al-Mulla, Donna K. Arnett, Folkert W. Asselbergs, Bjørn Olav Åsvold, John Attia, Bernhard Banas, Stefania Bandinelli, Lawrence J. Beilin, David A. Bennett, Tobias Bergler, Dwaipayan Bharadwaj, Ginevra Biino, Eric Boerwinkle, Carsten A. Böger, Judith B. Borja, Claude Bouchard, Donald W. Bowden, Ivan Brandslund, Ben Brumpton, Julie E. Buring, Mark J. Caulfield, John C. Chambers, Giriraj R. Chandak, Stephen J. Chanock, Nish Chaturvedi, Yii-Der Ida Chen, Zhengming Chen, Ching-Yu Cheng, Yoon Shin Cho, Kaare Christensen, Ingrid E. Christophersen, Marina Ciullo, John W. Cole, Francis S. Collins, Maria Pina Concas, Richard S. Cooper, Miguel Cruz, Francesco Cucca, Michael J. Cutler, Scott M. Damrauer, Thomas M. Dantoft, Gert J. de Borst, Eco J. C. de Geus, Lisette C. P. G. M. de Groot, Philip L. De Jager, Dominique P. V. de Kleijn, H. Janaka de Silva, George V. Dedoussis, Anneke I. den Hollander, Shufa Du, Douglas F. Easton, Kai-Uwe Eckardt, Petra J. M. Elders, A. Heather Eliassen, Patrick T. Ellinor, Sölve Elmståhl, Jeanette Erdmann, Michele K. Evans, Diane Fatkin, Bjarke Feenstra, Mary F. Feitosa, Luigi Ferrucci, Jose C. Florez, Ian Ford, Myriam Fornage, Andre Franke, Paul W. Franks, Barry I. Freedman, Christian Gieger, Giorgia Girotto, Yvonne M. Golightly, Clicerio Gonzalez-Villalpando, Penny Gordon-Larsen, Harald Grallert, Struan F. A. Grant, Niels Grarup, Lyn Griffiths, Vilmundur Gudnason, Christopher Haiman, Hakon Hakonarson, Torben Hansen, Catharina A. Hartman, Andrew T. Hattersley, Caroline Hayward, Iris M. Heid, Chew-Kiat Heng, Christian Hengstenberg, Karl-Heinz Herzig, Alex W. Hewitt, Haretsugu Hishigaki, David M. Hougaard, Carel B. Hoyng, Paul L. Huang, Wei Huang, Wen-Yi Huang, Jennifer E. Huffman, Steven C. Hunt, Nina Hutri, Kristian Hveem, Elina Hyppönen, William G. Iacono, Sahoko Ichihara, M. Arfan Ikram, Carmen R. Isasi, Marjo-Riitta Jarvelin, Zi-Bing Jin, Karl-Heinz Jöckel, Jost B. Jonas, Peter K. Joshi, Pekka Jousilahti, J. Wouter Jukema, Mika Kähönen, Yoichiro Kamatani, Kui Dong Kang, Jaakko Kaprio, Sharon L. R. Kardia, Fredrik Karpe, Norihiro Kato, Maryam Kavousi, Frank Kee, Thorsten Kessler, Amit V. Khera, Chiea Chuen Khor, Lambertus A. L. M. Kiemeney, Bong-Jo Kim, Eung Kweon Kim, Hyung-Lae Kim, Paulus Kirchhof, Mika Kivimaki, Woon-Puay Koh, Heikki A. Koistinen, Alexander Kokkinos, Jaspal S. Kooner, Charles Kooperberg, Peter Kovacs, Adriaan Kraaijeveld, Peter Kraft, Ronald M. Krauss, Meena Kumari, Zoltan Kutalik, Markku Laakso, Leslie A. Lange, Claudia Langenberg, Lenore J. Launer, Hyejin Lee, Nanette R. Lee, Terho Lehtimäki, Rozenn N. Lemaitre, Huaixing Li, Liming Li, Wolfgang Lieb, Xu Lin, Lars Lind, Allan Linneberg, Ching-Ti Liu, Jianjun Liu, Markus Loeffler, Barry London, Fan Lu, Steven A. Lubitz, David A. Mackey, Patrik K. E. Magnusson, JoAnn E. Manson, Gregory M. Marcus, Pedro Marques Vidal, Nicholas G. Martin, Winfried März, Fumihiko Matsuda, Mark I. McCarthy, Robert W. McGarrah, Matt McGue, Amy Jayne McKnight, Sarah E. Medland, Dan Mellström, Andres Metspalu, Braxton D. Mitchell, Paul Mitchell, Dennis O. Mook-Kanamori, Trevor A. Mori, Andrew D. Morris, Lorelei A. Mucci, Patricia B. Munroe, Mike A. Nalls, Saman Nazarian, Amanda E. Nelson, Matt J. Neville, Christopher Newton-Cheh, Christopher S. Nielsen, Harri Niinikoski, Kjell Nikus, Markus M. Nöthen, Adesola Ogunniyi, Claes Ohlsson, Albertine J. Oldehinkel, Lorena Orozco, Katja Pahkala, Päivi Pajukanta, Colin N. A. Palmer, Esteban J. Parra, Cristian Pattaro, Oluf Pedersen, Craig E. Pennell, Brenda W. J. H. Penninx, Louis Perusse, Annette Peters, Patricia A. Peyser, David J. Porteous, Danielle Posthuma, Chris Power, Peter P. Pramstaller, Michael A. Province, Bruce M. Psaty, Qibin Qi, Jia Qu, Daniel J. Rader, Olli T. Raitakari, Loukianos S. Rallidis, Dabeeru C. Rao, Susan Redline, Dermot F. Reilly, Alexander P. Reiner, Sang Youl Rhee, Paul M. Ridker, Michiel Rienstra, Samuli Ripatti, Marylyn D. Ritchie, Fernando Rivadeneira, Dan M. Roden, Frits R. Rosendaal, Jerome I. Rotter, Igor Rudan, Femke Rutters, Seungho Ryu, Charumathi Sabanayagam, Babatunde Salako, Danish Saleheen, Veikko Salomaa, Nilesh J. Samani, Dharambir K. Sanghera, Naveed Sattar, Börge Schmidt, Helena Schmidt, Reinhold Schmidt, Matthias B. Schulze, Heribert Schunkert, Laura J. Scott, Rodney J. Scott, Peter Sever, Wayne H. H. Sheu, M. Benjamin Shoemaker, Xiao-Ou Shu, Eleanor M. Simonsick, Mario Sims, Andrew B. Singleton, Moritz F. Sinner, J. Gustav Smith, Harold Snieder, Tim D. Spector, Beatrice Spedicati, Meir J. Stampfer, Klaus J. Stark, David P. Strachan, Yasuharu Tabara, E. Shyong Tai, Hua Tang, Jean-Claude Tardif, Thangavel A. Thanaraj, Anke Tönjes, Tiinamaija Tuomi, Jaakko Tuomilehto, Maria-Teresa Tusié-Luna, Rob M. van Dam, Pim van der Harst, Nathalie Van der Velde, Cornelia M. van Duijn, Natasja M. van Schoor, Veronique Vitart, Marie-Claude Vohl, Uwe Völker, Peter Vollenweider, Henry Völzke, Scott Vrieze, Niels H. Wacher-Rodarte, Mark Walker, Gurpreet S. Wander, Nicholas J. Wareham, Richard M. Watanabe, Hugh Watkins, David R. Weir, Thomas M. Werge, Elisabeth Widen, Gonneke Willemsen, Walter C. Willett, James F. Wilson, Peter W. F. Wilson, Tien Y. Wong, Jeong-Taek Woo, Alan F. Wright, Huichun Xu, Chittaranjan S. Yajnik, Jian Yang, Mitsuhiro Yokota, Jian-Min Yuan, Eleftheria Zeggini, Babette S. Zemel, Wei Zheng, Xiaofeng Zhu, M. Carola Zillikens, Alan B. Zonderman, John-Anker Zwart, DiscovEHR (DiscovEHR and MyCode Community Health Initiative), GPC-UGR, Understanding Society Scientific Group, VA Million Veteran Program, Goncalo R. Abecasis, Themistocles L. Assimes, Adam Auton, Michael Boehnke, Daniel I. Chasman, Tõnu Esko, Kari Stefansson, Guillaume Lettre, Cecilia M. Lindgren, Maggie C. Y. Ng, Christopher J. O’Donnell, Unnur Thorsteinsdottir, Peter M. Visscher, Robin G. Walters, Thomas W. Winkler, Andrew R. Wood, Panos Deloukas, Timothy M. Frayling, Anne E. Justice, Tuomas O. Kilpeläinen, Adam E. Locke, Karen L. Mohlke, Kari E. North, Yukinori Okada, Cristen J. Willer, Kristin L. Young, Segun Fatumo, Jeanne M. McCaffery, Nicholas J. Timpson, Joel N. Hirschhorn, Yan V. Sun, Sonja I. Berndt, Ruth J. F. Loos
Institutions: University of Copenhagen, Leiden University Medical Center, Novo Nordisk Foundation Center for Basic Metabolic Research, Icahn School of Medicine at Mount Sinai, University of Bristol, MRC Integrative Epidemiology Unit, Emory University, Atlanta VA Health Care System, Division of Cancer Epidemiology and Genetics, University of Michigan, Nanjing Medical University, The University of Queensland, Institute for Molecular Bioscience, Michigan Medicine, University of North Carolina at Chapel Hill, Geisinger Medical Center, Geisinger Health System, Vanderbilt University Medical Center, Queen Mary University of London, William Harvey Research Institute, Broad Institute, Brigham and Women's Hospital, Harvard University, RIKEN Center for Integrative Medical Sciences, The University of Osaka, University of Massachusetts Amherst, Boston Children's Hospital, Wake Forest University Health Sciences, Wake Forest University, University of Oxford, University of Exeter, Centre for Human Genetics, University of Tartu, Erasmus MC, RTI International, SIB Swiss Institute of Bioinformatics, University of Lausanne, Kyushu University, University of California San Diego, University of California, Los Angeles, Mental Health Services, Copenhagen University Hospital, Centre for Cellular and Molecular Biology, University of Washington, University of Helsinki, Institute for Molecular Medicine Finland, HiLIFE – Elämäntieteiden Instituutti, Children's Hospital of Philadelphia, Quantinuum (United States), University of Pennsylvania, University Hospital Regensburg, University of Regensburg, University of Leicester, Glenfield Hospital, NIHR Leicester Biomedical Research Centre, Medical College of Wisconsin, Statens Serum Institut, Vanderbilt University, University of Trieste, Institute of Genetics and Cancer, University of Edinburgh, Queen's University Belfast, National University of Singapore, National University Health System, King's College London, Université Laval, 23andMe (United States), Christian-Albrechts-Universität zu Kiel, Heidelberg University, Medizinische Fakultät Mannheim, University of Sassari, University of Surrey, Boston University, University of Peloponnese, Harokopio University of Athens, Agency for Science, Technology and Research, Genome Institute of Singapore, German Center for Diabetes Research, German Institute of Human Nutrition, Gentofte Hospital, Copenhagen Prospective Studies on Asthma in Childhood, University College London, National Institutes of Health, National Human Genome Research Institute, Institute for Social Research, National Institute of Genomic Medicine, Innsbruck Medical University, Universität Innsbruck, Institut für Medizinische Informatik, Biometrie und Epidemiologie, Essen University Hospital, U-M Rogel Cancer Center, Eurac Research, Institute for Biomedicine, Radboud University Medical Center, University of Mississippi, John Radcliffe Hospital, QIMR Berghofer Medical Research Institute, Aarhus University, Lundbeck Foundation, The Lundquist Institute, Harbor–UCLA Medical Center, Uppsala University, Fred Hutch Cancer Center, Rigshospitalet, Danish Multiple Sclerosis Center, Finnish Institute for Health and Welfare, Framingham Heart Study, Lund University, VA Boston Healthcare System, Medical University of Graz, University of Newcastle Australia, Leipzig University, Vrije Universiteit Amsterdam, Peking University, Southern University of Science and Technology, Massachusetts General Hospital, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Korea National Institute of Health, Taipei Veterans General Hospital, Otsuka (Japan), National Center for Global Health and Medicine, Amsterdam Neuroscience, Amsterdam UMC Location Vrije Universiteit Amsterdam, Umeå University, Frederiksberg Hospital, Center for Clinical Research and Prevention, University of Thessaly, University of Kelaniya, Kyoto University, Philadelphia VA Medical Center, The Queen's Medical Research Institute, Ewha Womans University, Samsung Medical Center, Research Institute for Future Medicine, Sungkyunkwan University, University of Toronto, Queensland University of Technology, Taichung Veterans General Hospital, Data Tecnica International (United States), National Institute on Aging, Leidos Biomedical Research Inc. (United States), St. Cloud State University, Case Western Reserve University, University of Massachusetts Chan Medical School, Montreal Heart Institute, Radboud University Nijmegen, University of Cambridge, MRC Epidemiology Unit, University of Bergen, Tampere University, Tampere University Hospital, Fimlab (Finland), University of Tampere, Dasman Diabetes Institute, National and Kapodistrian University of Athens, Guy's and St Thomas' NHS Foundation Trust, University of Virginia, Western General Hospital, MRC Human Genetics Unit, Dalhousie University, Institut für Psychiatrische Phänomik und Genomik, Ludwig-Maximilians-Universität München, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinikum Erlangen, Amsterdam Public Health, Amsterdam University Medical Centers, University Hospital Schleswig-Holstein, German Centre for Cardiovascular Research, University of Lübeck, University of Turku, Turku University Hospital, Nagoya University, University of Gothenburg, Korea Institute of Science and Technology, Lillebaelt Hospital, University Medical Center Groningen, University of Groningen, Wellcome Sanger Institute, Institute of Genetics and Biophysics, Vejle Sygehus, Algebra Bernays University, University of Split, Center for Non-Communicable Diseases, Helmholtz Munich, Hunter Medical Research Institute, University of Maryland, Baltimore, Instituto de Salud Carlos III, Karolinska Institutet, Centre for Biomedical Network Research on Rare Diseases, Institut de Recerca Sant Pau, IRCCS Materno Infantile Burlo Garofolo, Hallym University, Institute of Genetic and Biomedical Research, National Research Council, Amsterdam Cardiovascular Sciences, Icelandic Heart Association, Sahlgrenska University Hospital, Skåne University Hospital, deCODE Genetics (Iceland), Loyola University Chicago, Gladstone Institutes, VA Palo Alto Health Care System, Universitätsmedizin Greifswald, Universität Greifswald, University of California, San Francisco, Utrecht University, University Medical Center Utrecht, University of Amsterdam, Pennsylvania State University, Huazhong University of Science and Technology, Washington University in St. Louis, Beijing Tongren Hospital, Capital Medical University, University of Alabama at Birmingham, Information Management Services, MRC Centre for Environment and Health, Imperial College London, Medical University of Vienna, Oslo University Hospital, MRC Unit for Lifelong Health and Ageing, University of Freiburg, University Medical Center Freiburg, The University of Texas Health Science Center at Houston, Kurume University, Kurume University Medical Center, Rush University Medical Center, Westlake University, University of Minnesota, Weill Cornell Medical College in Qatar, Weill Cornell Medicine, Alexandria University, Deutsches Herzzentrum München, Technical University of Munich, Stanley Center for Psychiatric Research, Adolfo Ibáñez University, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Tecnológico de Monterrey, University of South Carolina, National Institute for Health and Care Research, UCL Biomedical Research Centre, Norwegian University of Science and Technology, St Olav's University Hospital, The University of Western Australia, Royal Perth Hospital, Jawaharlal Nehru University, Istituto di Genetica Molecolare, University of San Carlos, Pennington Biomedical Research Center, University of Southern Denmark, Imperial College Healthcare NHS Trust, Nanyang Technological University, Ealing Hospital, London North West Healthcare NHS Trust, Singapore National Eye Center, Singapore Eye Research Institute, Vestre Viken Hospital Trust, Istituto Neurologico Mediterraneo, Baltimore VA Medical Center, Mexican Social Security Institute, Centro Medico Nacional Siglo XXI, Intermountain Healthcare, Intermountain Medical Center, Wageningen University & Research, Columbia University Irving Medical Center, Columbia University, Charité - Universitätsmedizin Berlin, Victor Chang Cardiac Research Institute, UNSW Sydney, St Vincent's Hospital Sydney, University of Glasgow, University of Nebraska Medical Center, Instituto Nacional de Salud Pública, University of Iceland, University of Southern California, Poznan University of Medical Sciences, University of Oulu, Lions Eye Institute, University of Tasmania, The University of Melbourne, The Royal Victorian Eye & Ear Hospital, Centre for Eye Research Australia, Menzies Institute for Medical Research, Chinese National Human Genome Center, Chinese National Human Genome Center at Shanghai, Shanghai Industrial Technology Institute, University of Utah, University of South Australia, South Australian Health and Medical Research Institute, Jichi Medical University, Albert Einstein College of Medicine, Oulu University Hospital, Brunel University of London, Wenzhou Medical University, Affiliated Eye Hospital of Wenzhou Medical College, L V Prasad Eye Institute, Hôpital Rothschild, Fondation de Rothschild, Netherlands Heart Institute, The University of Tokyo, The Catholic University of Korea Incheon St. Mary's Hospital, Churchill Hospital, NIHR Oxford Biomedical Research Centre, Oxford Centre for Diabetes, Endocrinology and Metabolism, Verve Therapeutics (United States), Yonsei University, Yonsei University Health System, University Medical Center Hamburg-Eppendorf, Atrial Fibrillation NETwork, University of Birmingham, Helsinki University Hospital, Minerva Foundation, Laiko General Hospital of Athens, University Hospital Leipzig, University of Essex, Institute for Social and Economic Research, University of Eastern Finland, Kuopio University Hospital, University of Colorado Denver, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, University of Iowa Hospitals and Clinics, Centre Hospitalier Universitaire Vaudois, Synlab (Germany), Duke University, Duke Medical Center, The University of Sydney, Westmead Institute for Medical Research, Norwegian Institute of Public Health, University of Bonn, University Hospital Bonn, University of Ibadan, University of Dundee, Ninewells Hospital, Institut sur la nutrition et les aliments fonctionnels (INAF), Centre Nutrition, santé et société, Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Great Ormond Street Hospital, University General Hospital Attikon, Merck & Co., Inc., Rahway, NJ, USA (United States), Kyung Hee University, Kangbuk Samsung Hospital, Duke-NUS Medical School, University of Oklahoma Health Sciences Center, University of Potsdam, National Health Research Institutes, University of California, Riverside, LMU Klinikum, St George's, University of London, Stanford Medicine, Stanford University, Université de Montréal, Folkhälsans Forskningscentrum, King Abdulaziz University, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Universidad Nacional Autónoma de México, George Washington University, Amsterdam UMC Location University of Amsterdam, Newcastle University, Dayanand Medical College & Hospital, Beijing Tsinghua Chang Gung Hospital, Tsinghua University, University of Pittsburgh, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, TUM Klinikum, University of Oslo, Imam Abdulrahman Bin Faisal University, University of Geneva, MRC/UVRI & LSHTM Uganda Research Unit, Uganda Virus Research Institute, University of Connecticut
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $12,690
Funders: National Science Foundation, Foundation for the National Institutes of Health, U.S. Department of Veterans Affairs, Cancer Research Institute, Prostate Cancer Foundation, Juvenile Diabetes Research Foundation International, March of Dimes Foundation, Breast Cancer Research Foundation, Ovarian Cancer Research Fund, Amgen, Bristol-Myers Squibb, Eli Lilly and Company, Pfizer, AstraZeneca, Bayer, GlaxoSmithKline, Sanofi, Atlantic Philanthropies, Massachusetts General Hospital, Yale University, Gilead Sciences, Alexion Pharmaceuticals, Children's Hospital of Philadelphia, Vanderbilt University, University of Pennsylvania, Victor Chang Cardiac Research Institute, University of Michigan, Hjerteforeningen, Foundation for Cardiovascular Research, Danone, Helsingin Yliopisto, University of Washington, University of Oklahoma, University of Notre Dame, Case Western Reserve University, College of Medicine, University of Oklahoma, Takeda Pharmaceutical Company, Helsingin ja Uudenmaan Sairaanhoitopiiri, Boston Scientific Corporation, Harvard T.H. Chan School of Public Health, Deutsches Krebsforschungszentrum, National Cancer Research Institute, Movember Foundation, Genome Canada, Japan Agency for Medical Research and Development, Pancreatic Cancer UK, Regeneron Pharmaceuticals, Yrjö Jahnssonin Säätiö, Finska Läkaresällskapet, Wellcome Trust, Deutsches Zentrum für Herz-Kreislaufforschung, United Kingdom Clinical Research Collaboration, Scottish Government, Royal Marsden NHS Foundation Trust, National Center for Global Health and Medicine, Swedish Cancer Foundation, NorthShore University HealthSystem, Vanderbilt University Medical Center, Broad Institute, Government of the United Kingdom, Australian Government, Leidos, Folkhälsanin Tutkimussäätiö, Duke-NUS Medical School, Health~Holland, Fondation du cancer du sein du Québec, Department for the Economy, Janssen Scientific Affairs, Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Cotswold Foundation, Amsterdam University Medical Centers, Jan Dekker Stichting, Invitae, Government of Canada, Prostate Cancer Canada, National Institute for Health and Care Research, British Heart Foundation, Scottish Funding Council, University of Cambridge, European Commission, Rosetrees Trust, University of Glasgow, Queen's University Belfast, University of Bristol, Prostate Cancer Foundation of Australia, Women and Infants Research Foundation, National Research Foundation, Agency for Science, Technology and Research, National University of Singapore, National Research Foundation Singapore, Council of Scientific and Industrial Research, India, Centre for Ageing Research and Development in Ireland, Science Foundation Ireland, Public Health Agency, Deutsche Forschungsgemeinschaft, Fondation Leducq, Ministry of Education, Culture, Sports, Science and Technology, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Universiteit Leiden, Rijksuniversiteit Groningen, Stiftelsen för Strategisk Forskning, Danmarks Grundforskningsfond, Murdoch University, University of Notre Dame Australia, National Natural Science Foundation of China, ZonMw, Radboud Universiteit, Vrije Universiteit Amsterdam, National Science Council, Kela, Bundesministerium für Bildung und Forschung, Chinese Academy of Sciences, Austrian Science Fund, Kyung Hee University, Sungkyunkwan University, Generalitat de Catalunya, Gentofte Hospital, Dalhousie University, Nierstichting, Else Kröner-Fresenius-Stiftung, Suomen Kulttuurirahasto, Fonds Wetenschappelijk Onderzoek, Consejo Nacional de Ciencia y Tecnología, Ministero della Salute, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Lunds Universitet, Nederlandse Zuivel Organisatie, Queen's University, Ministero dell’Istruzione, dell’Università e della Ricerca, Lundbeckfonden, University of Toronto, Korea Institute of Science and Technology, National Research Foundation of Korea, Regione Campania, Juho Vainion Säätiö, Karolinska Institutet, Oesterreichische Nationalbank, Knut och Alice Wallenbergs Stiftelse, Universität zu Lübeck, Novo Nordisk, Universität Potsdam, Signe ja Ane Gyllenbergin Säätiö, Stockholms Läns Landsting, Office of the First Minister and Deputy First Minister, National Health Research Institutes, Emil Aaltosen Säätiö, Samfundet Folkhälsan, Ministerio de Ciencia e Innovación, Instituto Mexicano del Seguro Social, Umeå Universitet, Augustinus Fonden, Universitetet i Bergen, Leids Universitair Medisch Centrum, Universitair Medisch Centrum Groningen, Rigshospitalet, National and Kapodistrian University of Athens, Universitätsklinikum Regensburg, Fundación IMSS, Dasman Diabetes Institute, Norges Forskningsråd, Turun Yliopisto, Sydäntutkimussäätiö, Universität Hamburg, Technische Universität München, Ludwig-Maximilians-Universität München, Lastentautien Tutkimussäätiö, Sahlgrenska Universitetssjukhuset, Göteborgs Universitet, Deutsche Herzstiftung, Deutsche Krebshilfe, Center for Translational Molecular Medicine, Department of Health, Government of Western Australia, Oulun Yliopisto, Radboud Universitair Medisch Centrum, Institut National Du Cancer, Tampereen Tuberkuloosisäätiö, National Institute of Biomedical Innovation, Otsuka Pharmaceutical, Medical Research Council Canada, TrygFonden, Gratama Stichting, Wetenschappelijk Onderzoek- en Documentatiecentrum, Peking University, Diabetesliitto, Paavo Nurmen Säätiö, Universität Leipzig, Karl-Franzens-Universität Graz, Safe Work Australia, Faculty of Health and Medical Sciences, University of Western Australia, Oogfonds, Novo Nordisk Fonden, Chinese Society of Clinical Oncology, Egmont Fonden, Taichung Veterans General Hospital, Medizinische Universität Graz, Landelijke Stichting voor Blinden en Slechtzienden, Stichting Blindenhulp, Tays, University of Thessaly, Syöpäsäätiö, Government of Western Australia, Skånes universitetssjukhus, University of Chinese Academy of Sciences, University of Kelaniya, Siemens Healthineers, Servier, National University Health System, Turun Yliopistollinen Keskussairaala, Vlaamse regering, Taipei Veterans General Hospital, Mitsubishi Tanabe Pharma Corporation, Southern University of Science and Technology, Fondation Institut de Cardiologie de Montréal, Institut de Cardiologie de Montréal, Hjartavernd, H. Lundbeck A/S, Diabetestutkimussäätiö, Xarxa de Bancs de Tumors de Catalunya, Freistaat Sachsen, Provincia autonoma di Bolzano - Alto Adige, KfH-Stiftung Präventivmedizin, Vincent Fairfax Family Foundation, Heinz Nixdorf Stiftung, Diabetesforeningen, Fundación Marqués de Valdecilla, Amsterdam Neuroscience, Sygehus Lillebælt, Turun Yliopistosäätiö, National Institutes of Health, Centers for Disease Control and Prevention, Samsung, University of Oklahoma Health Sciences Center, Perelman School of Medicine, University of Pennsylvania, Wake Forest School of Medicine, Abbott Diagnostics, Helsinki Institute of Life Science, Helsingin Yliopisto, Elizabeth Blackwell Institute for Health Research, University of Bristol, Canadian Institutes of Health Research, Canadian Cancer Society Research Institute, Medical Research Council, Economic and Social Research Council, Cancer Council Victoria, National Medical Research Council, Korea National Institute of Health, St. George's, University of London, Instituto de Salud Carlos III, Wageningen University and Research, Sahlgrenska Akademin, Helse Sør-Øst RHF, Det Sundhedsvidenskabelige Fakultet, Københavns Universitet, Departament d'Universitats, Recerca i Societat de la Informació, Health and Social Care Research and Development Division, National Key Research and Development Program of China, China-Japan Friendship Hospital, Biomedical Research Council, Helmholtz Zentrum München, Faculty of Medicine and Health, University of Sydney, National Institute on Alcohol Abuse and Alcoholism, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute on Drug Abuse, National Human Genome Research Institute, National Eye Institute, National Cancer Institute, National Institute of Nursing Research, National Institute of General Medical Sciences, Fogarty International Center, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, National Institute of Environmental Health Sciences, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Center for Research Resources, National Center for Chronic Disease Prevention and Health Promotion, National Center for Advancing Translational Sciences, National Institute on Minority Health and Health Disparities, Biosense Webster, Eunice Kennedy Shriver National Institute of Child Health and Human Development, UCB Pharma, Institute of Genetics, Core Research for Evolutional Science and Technology, Center of Innovation Program, JST-Mirai Program
Awards: G1004914174, G10106230, G1017297203, G1019533026, G1027239709, G105512408, G1069732457, G1070416740, G1080192134, G1096603473, G1110316427, G1114307781, G1116937713, G1127799983, G1153974796, G1154299264, G1160275816, G116534467, G1178407541, G1180467953, G1188375265, Family Blood Pressure Program (GenNet Network), G1206754599, A genome-wide association study for breast cancer in BRCA1 mutation carriers, G1220223050, G1222188272, G1227813248, G1242691555, G1248102086, G1260873166, G1261314546, G127234364, Identifying Contributions of Pulmonary Inflammation to Sleep-Disordered Breathing, Genetic & epigenetic analysis of angiogenesis genes in recurrent prostate cancer, G1284367791, G1289731471, G1294880572, G1299732660, G1307706216, G1309204960, G1327305488, G1332411685, G1338396984, The Genetics of Vulnerability to Nicotine Addictions, EHR-based Genomic Discovery and Implementation, G1378522051, G1398898637, Polygenic prediction of common, complex diseases, G1409423729, G1423781327, G1429306515, G144106340, G1458435566, G1463724070, G1481280302, G1532938828, G1539384734, G1551168579, G1561916549, G1584405745, G158574770, G1612023617, G1614944260, G16286648, G165068080, G1658243001, G1666450717, G1673242160, G1686417863, G1704434335, G176066355, G1769755554, G1789381357, G1789756995, G1795870773, G1803853571, G1805920007, G1815215131, G1826260630, G1840895289, G1863755600, PROSTATE CANCER IN RELATION TO VASECTOMY, G1873219037, G1900157527, G190379715, G1910112017, Cardiovascular diseases and psychiatric disorders in the general population: a prospective follow-up study, Studies of Occupational Cancer (Pesticides), G1951867125, G1961143727, G1967470738, G1979271746, Centre for Longitudinal Studies, Resource Centre 2015-20, Genome-wide case-only study of antihypertensive drug-gene interactions, G2030104575, G2045551132, G2059721671, Monitoring Social Change: Dynamics Of Aging And Cognitive Function, G20691538, G2069482854, G2076123899, G2076485198, G2081319657, G208977833, G2105629783, G2115812462, G2127676537, G2169105496, G217261670, G2176455653, G2194386449, G2214254730, Understanding the genetic risk underlying racial disparities in uterine fibroids, G221869912, G2223568566, G2247787434, G2249728113, G2256198775, G2262782284, G2268797580, Genetic Architecture of Adiposity in Multiple Large Cohorts, G2280445022, G2283396561, G229684361, Cardiovascular diseases and psychiatric disorders in the general population: a prospective follow-up study, Population pharmacogenetics of statin response., G2308453067, G2310098089, G2311604725, G2313542652, G2316258288, G232264632, G2327766872, G2328519459, G2391884931, G2393046502, G2396294839, G2404662676, G2415573643, New methods for constructing and evaluating polygenic scores, G2437620908, G2464355595, Health behaviors over the adult lifecourse and cognitive aging, G247538147, G2478079187, G2481876672, G2486088282, G2487849073, G2528054427, G2530187302, G2539059078, G25420283, G2548880556, G2553889976, G2576085165, G2580996367, G2581532355, G2597118879, G2601817178, G2604599836, G2620658983, G2628120876, G2647818892, G2648688395, G271331228, G2718683818, G2730950932, G2741792843, G2746122734, G2750614948, G2758235907, G2769288755, THE SINGAPORE COHORT STUDY OF DIET AND CANCER, G278200998, G2787469147, G2788466971, G2809357584, G2816908038, G2820054027, Genetic Association Meta-Analyses of Smoking and Drinking for the Sequencing Age, G2854377419, G2856445237, G2857511458, G2870375487, G287178428, G2908460189, G2920419711, G2922038998, G2932130186, G294025628, G2957143966, G2970637568, G297113894, G3000638811, G3005741272, G3009016685, G3033840998, G3037546023, G3045517347, G3085877500, GENETIC SUSCEPTIBILITY TO CANCER IN MULTIETHNIC COHORTS, The knowledge culture of business administration. Success and dilemma of a hybrid discipline, G3110832977, 05/16 Action for Health in Diabetes Extension Study - Research Project, G3121967442, G3145302650, PCPT and SELECT cohorts: Core Infrastructure Support for Cancer Research, G3174308905, G3183394738, G3220743633, G3226071987, G3226476464, G3226771441, G3237517486, G3248287424, G3253097015, G3256118428, G3257671700, G3263306511, G3276551827, G3284250915, G3312959103, G3324502409, Familial Aggregation and Natural History of Sleep Apnea, G3342643523, G3344484334, G335053239, G3351215478, G3352865368, G3354324101, G3358115392, G3362311673, G3405256882, G3405515844, G3420921512, G3426488059, G3435429024, G343705321, G3450909657, G3478357739, G3478977405, G350245564, G3523811237, CHS research resources for the cardiovascular health of older adults, G3548295844, G3555325704, G3570589137, G3601521474, Fuzzy logic modelling of lithium kinetics and dynamics, G3607452959, G3617590231, G362537736, G3635063837, Better Outcomes for Children: Promoting Excellence in Healthcare Genomics to Inform Policy, G3646513721, G3647016462, Statistical methods for analyzing high-throughput genotype and sequencing data, G3655053135, G367799596, G3680082150, G368714643, G3687594596, Polygenic Risk Scores for Diverse Populations - Bridging Research and Clinical Care, G3722200205, G3728863030, G3738692396, G3743240706, G3754151977, G3763011920, Elucidating Loci Involved in Prostate Cancer Suceptibility, G3771020718, G3783191424, G3787614294, G3796770245, G3807225764, G3820875754, G3830541857, G3839646794, G3856074833, Pathway discovery, validation and compound identification for Alzheimer's disease, G3881485945, G3882732315, Genetics of Type 2 Diabetes in Indian Populations: US-India Collaboration Project, G3901643820, G3912115555, G3918807088, Genome Wide Association Study of Bone Mineral Accretion During Childhood, G393774532, Dietary and Hormonal Determinants of Cancer in Women, G3969377022, G3973572274, G3978296121, G3988842916, G399481048, G4017072919, G4027780594, G4028311180, Genetic Mechanisms of Arteriosclerosis in Hypertensive Sibships, G4064058321, Big Omics Data Engine 2 Supercomputer, G4119975330, G4123344822, G4127946622, PAGE III: Population Architecture using Genomics and Epidemiology, G4156535370, G4240498284, G4263251407, G4288653450, G4333521878, A Multi-Ancestry Study of Gene-Lifestyle Interactions and Multi-Omics in Cardiometabolic Traits, G4352572889, G4386962905, G4405986302, G4407350458, G4429312988, G4450071017, G4458374387, G4471409110, G4487394458, G4502495630, G4507648799, G4512137732, G4515907142, G4526427972, G4561499809, G4563812999, Genome Wide Association Coordinating Center, G4578992035, G459566519, G4612446324, G4623107666, G4652745033, G4672149634, G4675236536, What lies behind the causal impact of body mass index (BMI) level and change on human health? Added value from complementary study design and deep metabolomic phenotyping., G4694539458, G4708679710, G471519714, G47192932, G4747441672, G474757791, G475755283, G4758570167, G4760797969, G476489484, G4770402659, G4790942633, G479225836, G4801199537, G4802923568, Molecular Epidemiology of Alcoholism 1: Candidate Gene, G4816101164, G482433192, G483429595, Genome-wide association study of coronary artery diseases in individuals of African ancestry, G4869137933, G4870753963, G492660439, G4940423171, G494123624, G4991056325, G4991908250, G4995148504, G4996985803, Today's youth is tomorrow's workforce: generation Y at work (GenY@work), G5019474394, G50331642, G504460986, BioVU Plasma Storage Equipment, G5088122703, G5108002584, G5113654357, G5130508838, G513288951, G514410172, G5161585833, G5164707915, G5181373253, G5208162737, G5243773420, G5270826263, G5271203475, G5286450406, 09/16 Action for Health in Diabetes Extension Study Research Project, G5341903963, G5350642880, G5356134080, G5359555627, G536099884, G5365244667, G5388449085, G5390383492, G5418383269, Integrating genome-scale data to reveal causal mechanisms in type 2 diabetes, Genome-Wide Association for Loci Influencing CHD and Other Heart, Lung and Blood, G5435666231, G5437097169, G544054545, G5479317095, G5486405922, G5578384164, Study of the genetic variations in the TMPRSS2 control regions and their effects on prostate cancer development ., G5599442719, G5613623313, 08/16 Action for Health in Diabetes Extension Study Research Project, G5646142476, G5646618515, A national DNA control series for genetic case-control studies based on the British 1958 birth cohort, G568925064, Genomics of dyslipidemia in Mexicans, G5714867875, G571830633, G573982542, G5747968190, G5770678025, G5786101834, G5787256936, G5789723807, G579045871, G5800301348, G581887176, G5843173653, G5850682332, BEHAVIORAL PRECURSORS OF ALCOHOLISM--TWIN FAMILY STUDIES, G589846866, G5928944960, Accelerator Award, Genetic Risk to Stroke in Smokers and Nonsmokers in Two Ethnic Groups, G5942132429, G5986437587, Genetic Epidemiology of Multiple Sclerosis, CHS Events Follow-up Study, G6008837376, G6028199577, G6044760167, G6066892457, G6075306088, G6077436397, G6095866717, G6100683030, G612521529, G6129226368, G6140938529, G6166209737, Genetics of Cerebral Small Vessel Disease, G617038295, Growth Factors and Lethal Prostate Cancer Signature, G6182174406, G622191773, G6226795708, G6238440229, G6296843930, G6302472787, G6321997688, G6328075693, G6359107525, Institute for Clinical and Translational Research, G6413938271, NSAIDS and Other Medications in Prostate Cancer Etiology, Understanding Society: The UK Household Longitudinal Survey Waves 13-15, G6476066419, G6505221676, G6514094751, G6515215265, G6543636935, G656756306, CNV And Stroke (CaNVAS), G6599896107, G6628312008, G6637869296, G6654466364, G6663973959, G6668479156, G6681950725, G668427470, Identification of genetic variants underlying coronary artery disease and associated phenotypes in Indian Asians., G6744055134, G675132270, G6755603029, G6757907, G6790783885, G6837735701, G6844745840, G6847200547, G6875046544, G6887972972, G6894818919, G6898856972, G6904192639, G6908972008, G6927407676, Cambridge Institute for Medical Research (CIMR)., Mid-Atlantic Nutrition Obesity Research Center, G7006486244, G7032370290, G7040426476, G7091571603, Obesity development and CVD risk factor clustering in Filipino women & offspring, G7144126959, G7147294205, G7155745631, G716312657, G7176672723, G7232005456, G724245799, G7244940528, G7245015376, G7262634952, G7267526003, G7271263264, Cardiovascular diseases and psychiatric disorders in the general population: a prospective follow-up study, G7304741505, G731149954, G7331169431, G7333524540, G7352723158, G7376939847, Cancer epidemiology cohorts in Shanghai and Singapore , MRI white matter abnormalities in the elderly: Genetic risk factors, rate of progression and neuropsychologic consequences, Genetic Modulators of Sudden Death, Netherlands Twin Registry Repository: researching the interplay between genome and environment, G7475101988, G7518182772, Adolescent Alcohol Abuse: A Twin-Study Perspective, G7535686976, G7579064381, G7595421264, NHLBI FAMILY BLOOD PRESSURE PROGRAM (GENOA), LUDC-IRC för individanpassad medicin i diabetes, G7632654634, G7684595986, G7685529176, G7691823121, Derivation and validation of a risk model for prediction of cardiovascular disease events in UK Indian Asians, G7697152668, G7726777033, The Vanderbilt Institute for Clinical and Translational Research (VICTR), G7785699384, MULTIPURPOSE ARTHRITIS &MUSCULOSKELETAL DISEASES CENTER, G781900440, G7821233859, Functional Interrogation of T2D-associated genes in human stem cell-derived models and mice, ReliabilitY of opto-Transceivers for Health Monitoring Systems, G7874299154, G7879866177, Women's Health Study: Continued Follow-up, G7924683342, COVID and Translational Science supercomputer (CATS), G7975901996, Integración de big data genéticos y datos clínicos: supervivencia con cáncer de mama en el estudio MCC-Spain, Twin Family Study of Vulnerability to Substance Abuse, G8038921994, G8058067277, Clinical and Translational Science Award, G8111550955, G8123125509, G8125002010, G814381192, G814392139, G8148345956, G8157173948, G816910144, G8253295407, G8254542482, G8263226176, G8266149577, G8267674335, G828200374, G8323797553, G8325934978, Epidemiologic Architecture for Genes Linked to Environment (EAGLE), G8337188992, G8337850540, 12/16 Action for Health in Diabetes Extension Study Research Project, G836417160, G8370481907, Immune targets for the treatment of atrial fibrillation, G8384987212, G8446680376, G8454377152, G8470176696, G8482826862, G8489272338, Risk Factors, Pathology, and Clinical Expressions of AD, G8499801373, G850960841, G855454396, PERSISTENCE AND CHANGE IN DRINKING HABITS--TWIN STUDY, G858805679, Cardiovascular diseases and psychiatric disorders in the general population: a prospective follow-up study, G859169766, Genetics of Early Onset-Stroke, G8638928368, Understanding Society and the UK Longitudinal Studies Centre, The Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) - CAPI, G872696599, HISPANIC SECONDARY STROKE PREVENTION INITIATIVE, G8738262636, G8761005068, G88327988, G8836210513, DNA Sequencing Support for the eMERGE Network, G8881436292, G8924490982, The Family Blood Pressure Program (GENOA Network), G896909551, G89699440, The genetics of weight, BMI, adiposity and obesity, G9000102603, G9000110503, Tracking Young Adults: wave six of the TRAILS study, G9000141698, G9000334979, Biological Insights from Genetic Investigation of ANthropometric Traits (GIANT) Across the Allelic Spectrum, Molecular and Cellular Basis for Digestive Diseases, Dissecting cell type-specific genetic programming of islet (dys)function in type 2 diabetes, Methods to unveil sex-specific genetic architecture in trans-ancestry meta-analysis, Enabling improved applicability and transferability of polygenic scores across populations, Cancer Center Support Grant, PLCO Trial Etiologic and Early Marker Study, Cardiovascular Epidemiology Training Grant, BCX-Africa: Utilizing data science to evaluate the applicability of blood cell traits polygenic risk scores for disease prediction in Africa, Nutrition Obesity Research Center (NORC), From GWAS loci to blood pressure genes, variants & mechanisms - Renewal, Human Factors of Aging Program, G905179811, G913983815, G931818222, G942818495, G944581649, G94668252, G949362299, G95160140, Families, households and health in ageing populations: Projections and implications
OpenAlex ID: W4412515005