Work

Digital twins in personalized medicine: Insights from a systematic review

Year: 2025
Type: review
Study design: Systematic Review
Abstract: Objectives: Digital twins (DTs) are increasingly recognized as valuable tools in the advancement of personalized medicine (PM). Methods: This systematic review explores the current landscape of DT applications across medical domains, focusing on their feasibility, benefits, challenges, and potential future roles. Following PRISMA guidelines, literature was sourced from PubMed and Scopus using clearly defined inclusion and exclusion criteria, resulting in 14 studies eligible for full-text review. Results: Findings show that DTs are being utilized in various specialties such as cardiology, geriatrics, radiology, and oncology, offering advantages in cost reduction, treatment precision, and patient outcomes. However, key challenges remain, including data privacy, technical integration, ethical considerations, and the need for interdisciplinary collaboration. Conclusions: This systematic review offers a comprehensive synthesis of how DTs are being integrated into PM and highlights areas requiring further empirical research to support wider implementation.
Author: Ebru Uğraş
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4412699366
FWCI:
Cites: 37
Cited by:
Related to: 10