Synthesis of 3-hydroxy-4-{[(2E)-2-(hydroxyimino)ethylidene]amino}-naphthalene-1-sulfonic acid for Complex formation of Cr3+, Co2+, Ni2+ and Cu2+ ions
Year: 2025
Type: article
Abstract: Purpose: This study aimed to synthesize and characterize new Schiff-base complexes derived from 3-hydroxy-4-{[(2E)-2-(hydroxyimino)ethylidene]amino}-naphthalene-1-sulfonic acid and to evaluate their structural properties and antimicrobial activity. Materials and Methods: The complexes of Cr³⁺, Co²⁺, Ni²⁺, and Cu²⁺ were synthesized and characterized using IR spectroscopy, molar conductivity, UV-Vis spectroscopy, magnetic susceptibility measurements, and elemental analysis (C, H, N, and S). The coordination behavior of the ligand was investigated based on spectral and magnetic data. Results: Elemental analysis confirmed a 1:1 metal-to-ligand stoichiometry in all complexes. Molar conductivity values indicated that the complexes are non-electrolytic. Magnetic moment data revealed that the Ni²⁺ complex is diamagnetic, while Co²⁺, Cr³⁺, and Cu²⁺ complexes are paramagnetic. IR spectral data suggested coordination through the hydroxyl and imino groups. Electronic spectra showed n→π* and π→π* transitions, supporting octahedral geometry for all complexes. Conclusion:The structural analysis confirmed the formation of stable, octahedral Schiff-base metal complexes. These compounds, including the free ligand, demonstrated notable antimicrobial activity against pathogenic bacteria such as Proteus, Bacillus subtilis, Staphylococci, and Pseudomonas aeruginosa.
Authors: Sarah Mukhtar, Arabya Almutaleb, Abdusalam Hamil, Khalifa Khalifa, Y. A. Alkhayali, Shamsi. Saad
Institution: Sebha University
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4412701366