Criteria for classifying children into risk groups according to atherosclerotic cardiovascular diseases
Year: 2025
Type: article
Abstract: Atherosclerosis, which begins early in life, accounts for a significant share of cardiovascular diseases in adulthood. At the same time, the prevalence of obesity, high blood pressure and dyslipidemia among children in certain regions of the Russian Federation reaches double figures. New order No. 211n of the Ministry of Health of Russia provides for the targeted lipid screening of children aged 6 and 10 years, however specific clinical and anamnestic grounds and criteria for being qualified as children at risk have not yet been regulated. This paper presents an analytical review of federal regulatory acts, current clinical guidelines and national multicenter studies (2014–2024), which gave rise to a list of indications for targeted screening for lipid profile in children and adolescents. The proposed checklist includes 17 clinical, anamnestic and phenotypic criteria grouped into eight blocks: (1) hereditary predisposition, (2) phenotypic markers for hyperlipidemia, (3) the presence of overweight/obesity, (4) resistant hypertension, (5) severe metabolic and systemic diseases, (6) congenital and acquired valvular heart diseases, (7) modifiable behavioural factors, (8) earlier cardiotoxic conditions. The presence of one key or two additional symptoms serves as a basis for an extended lipid panel testing and subsequent follow-up care. The presented model does not have a regulatory status and reflects the point of view of the authors' team; it is intended for expert discussion, improvement and further clinical validation. The proposed tool can be easily integrated into electronic health records, automating patient routing and creating the groundwork for prospective studies of Russian pediatric cohorts.
DOI: 10.21518/ms2025-275
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4412930779