Endobronchial solitary fibrous tumor: A case report with comprehensive literature review
Year: 2025
Type: article
Abstract: INTRODUCTION AND IMPORTANCE: Endobronchial solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that account for less than 2 % of all SFTs. Diagnosis and treatment are major challenges because of their rarity and varied presentation. We present a case of endobronchial SFT that was successfully treated with minimally invasive bronchoscopic excision and review the literature to highlight the latest developments in diagnosis and treatment. CASE PRESENTATION: A 45-year-old female was referred for an incidental finding of bronchial lesion on imaging. Chest computed tomography (CT) revealed a well-defined, noncalcified, obstructive lesion in the left upper lobe bronchus. Flexible bronchoscopy confirmed complete airway obstruction, and the tumor was excised using a hot snare. Histopathological examination revealed a low-risk solitary fibrous tumor with immunohistochemical positivity for CD34 and Bcl-2, confirming SFT. Follow-up imaging and clinical follow-up for three years showed no recurrence. CLINICAL DISCUSSION: We highlight the relevance of advanced imaging, histopathological examination, and multimodal management for the diagnosis and treatment of endobronchial SFTs. Minimally invasive bronchoscopic excision is a safe and effective treatment modality for localized lesions. CONCLUSION: This literature review underlines the need for long-term surveillance because of the tendency for malignant transformation. Documenting these infrequent cases improves diagnostic and therapeutic strategies for endobronchial SFTs.
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,090
OpenAlex ID: W4413720522