Work

Development of medullary thyroid carcinoma on a toxic nodule: about an exceptional case

Year: 2025

Type: article

Abstract: We report the case of a 60-year-old hypertensive female patient who presented with an anterior neck swelling associated with local compression signs. TSH levels were in favor of hyperthyroidism. Cervical ultrasound showed two nodules classified as EU-TIRADS III, one of which, located at the lower right pole, was hyperfunctioning on I-123 scintigraphy. After total thyroidectomy, the histopathological study confirmed that the toxic nodule corresponded to a medullary thyroid carcinoma. Calcitonin levels were 115.6 ng/L (N < 10 ng/L). The staging workup, as well as the MEN screening, were unremarkable. An extensive lymph node dissection was performed, revealing no lymph node involvement.

Source: Oxford Medical Case Reports

DOI: 10.1093/omcr/omaf178

Authors: Ali Halouache, Lahoussaine Abainou, Hajar Agouri, Mohammed Tbouda, Ismael Nakkabi

Language: English

Topic: Thyroid Cancer Diagnosis and Treatment

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,103

OpenAlex ID: W4414577657