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28P Circulating tumor DNA antedates breast cancer loco-regional recurrence: A proof-of-concept study

Year: 2025

Type: article

Abstract: Loco-regional recurrence (LRR) poses a clinical challenge for the follow-up of patients treated with curative intent for early-stage breast cancer (EBC). While circulating tumor DNA (ctDNA) has been shown to predict distant metastases, its value for LRR is less characterized.

Source: ESMO Open

DOI: 10.1016/j.esmoop.2025.105604

Authors: V. Appierto, E. Tamborini, P. Tiberio, A. Busico, L. De Cecco, M. Silvestri, C. De Marco, E. Cavadini, M.C. De Santis, S. Folli, G. Scaperrotta, A. Vingiani, G. Pruneri, S. Di Cosimo

Institutions: Fondazione IRCCS Istituto Nazionale dei Tumori, IRCCS Humanitas Research Hospital

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,910

Funder: National Natural Science Foundation of China

Award: G5424074244

OpenAlex ID: W4414710066

FWCI:

Cites:

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