Supplementary Tables S1-S12 from Germline–Somatic Liaison Dictates Cancer Subtypes via de novo Steroid Biosynthesis
Year: 2025
Type: supplementary-materials
Abstract: The supplementary table file includes Supplementary Tables S1-S12. Descriptions of each table are as follows: - Supplementary Table 1: Study oligo sequences - Supplementary Table 2: Number of Off Targets calculated with Cas-OFFinder for the final set of guides. - Supplementary Table 3: Description of three sets of deletion editing experiements in prostate cells - Supplementary Table 4: List of study DEGs - all comparisons - Supplementary Table 5: Results of AG vs GG differential analysis (PC3 cells, single clones) - Supplementary Table 6: Results of AA vs GG differential analysis (PC3 cells, single clones) - Supplementary Table 7: Human tissue RNA-seq differential analysis for SPOPmut vs SPOPwt (AA vs AG and AG vs GG clone data DEG set) - Supplementary Table 8: GO analysis of AG vs GG DEGs - Supplementary Table 9: Sample names conversion and annotation - Supplementary Table 10: RNA sequencing statistics - Supplementary Table 11: List of antibodies used in this study - Supplementary Table 12: LC-MS/MS Steroid detection
Authors: Paola Gasperini, Alessandro Alaimo, Blerta Stringa, Yoon-Mi Chung, Yari Ciani, Francesca Lorenzin, Giulia Fracassi, Yanis Zekri, Francesco Orlando, Orsetta Quaini, Sebastian Gregoricchio, Gianluca Petris, Antonio Casini, Christopher E. Barbieri, Wilbert Zwart, Anna Cereseto, Nima Sharifi, Andrea Lunardi, Francesca Demichelis
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4414846243