Work

Apremilast attenuates methotrexate-induced hepatic injury in rats; insights into TLR4/NF-κB/P38 MAPK/caspase-3 and α-klotho/Nrf2/HO-1 signaling network interplay

Year: 2025

Type: article

Source: Toxicology and Applied Pharmacology

DOI: 10.1016/j.taap.2025.117596

Authors: Reham H. Mohyeldin, Ehab E. Sharata, Mahmoud Abdelnaser, Ayman M. Ibrahim, Mina Ezzat Attya, Al Shaimaa Mahmoud Kotb, Ahmed S.Aboalela, Remon Roshdy Rofaeil

Institutions: Deraya University, Minia University, Galala University

Language: English

Topic: Drug-Induced Hepatotoxicity and Protection

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4415080486

FWCI: 10.98

Cites: 75

Cited by: 21

Related to: 10