Prospective Study on Effectiveness of GATT Alone or Combined with Phacoemulsification in Patients with Primary Open-Angle, Pseudoexfoliative, and Primary Angle-Closure Glaucoma
Year: 2025
Type: article
Abstract: Purpose: To evaluate the effectiveness of gonioscopy-assisted transluminal trabeculotomy (GATT), alone or combined with phacoemulsification, in patients with primary open-angle glaucoma (POAG), pseudoexfoliative glaucoma (PEXG), and primary angle-closure glaucoma (PACG) in a three-month prospective follow-up.Methods: Prospective clinical study conducted at "Instituto de la Visión" between 2023 and 2024.Twenty-seven eyes were included: POAG (n=13), PEXG (n=9), and PACG (n=5), treated with GATT alone or GATT + phacoemulsification.Outcomes included intraocular pressure (IOP), number of hypotensive medications, best-corrected visual acuity (BCVA), and visual field mean deviation (MD).Paired t-tests were used for comparison; p<0.05 was considered significant.Results: A significant IOP reduction was observed in POAG and PEXG groups (-37.9% and -58.5%, p<0.05), with a decrease in medication use of 64.7% and 66.7%, respectively.In the PACG group, IOP reduction was not statistically significant.The greatest IOP reduction occurred in the GATT-only group (-58.2%).BCVA remained stable.The most frequent complication was mild, self-limited hyphema.Conclusions: GATT, either standalone or combined with phacoemulsification, is a safe and effective surgical option for patients with primary glaucomas, particularly in POAG and PEXG, allowing for significant pressure reduction and medication burden relief.
Source: JOJ Ophthalmology
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4415567006