Work

Clinical manifestations and treatment of peripheral odontogenic keratocysts: two cases and a literature review

Year: 2025

Type: article

Abstract: BACKGROUND: Peripheral odontogenic keratocyst (POKC) is a rare extraosseous manifestation of odontogenic keratocyst (OKC). Because of their anatomical locations, OKCs and POKCs necessitate slightly different treatment approaches. However, the reported literature has not yet reached a definitive conclusion on this matter. METHODS: This study included 2 patients who experienced postoperative recurrence of POKCs in the right buccal mucosa from 2018 to 2020. Additionally, we reviewed the reported cases and summarized the clinical features, treatment and prognosis of the POKCs. RESULTS: The two patients with POKCs in this report experienced recurrence after the first surgery, and the second operation involved microscopic excision of the lesion with its adherent tissue. No recurrence was observed. CONCLUSIONS: Because POKCs are located in the soft tissue, they are difficult to remove and therefore prone to recur. In the treatment of POKCs, the surrounding adhesions can also be removed. Microscopic excision should be performed as well.

Source: Orphanet Journal of Rare Diseases

DOI: 10.1186/s13023-025-04087-3

Authors: Yu Huang, Lirui Zhang, Xiaohong Yuan, Zhien Feng

Institution: Capital Medical University

Language: English

Topic: Oral and Maxillofacial Pathology

Subfield: Oral Surgery

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,990