Observance et maladie rénale chronique : aspects psychologiques, déterminants et leviers potentiels
Year: 2025
Type: article
Abstract: Non-adherence to treatment affects 30% to 50% of patients with chronic diseases. It is associated with an increase in the frequency of acute complications and hospitalizations. In chronic kidney disease (CKD), non-adherence concerns drug treatment, diet, and lifestyle. It may affect up to 62% of hemodialysis patients and 28% of kidney transplant recipients. The long asymptomatic phase of CKD contrasts with a heavy medication burden—two factors that can hinder treatment adherence. In addition, the high prevalence of cognitive and depressive disorders, often underdiagnosed, is associated with the risk of non-adherence in CKD patients. Young age and social isolation have also been identified as risk factors. However, adherence is often difficult to assess. It may vary from one patient to the other, and in the same patient over the course of the disease. Non-adherence can sometimes reflect underlying psychological, personal, or social difficulties. Every health care professional involved in the care of CKD patients has a role to play in detecting poor adherence. In this general review, we discuss the psychological and medical aspects underlying non-adherence, as well as potential therapeutic levers.
Source: Néphrologie & Thérapeutique
DOI: 10.1684/ndt.2025.145
Authors: Stanislas Bobot, Valentine Cazauvieilh, Flora Lefèvre, Justine Solignac, Safia Mecerli, Safia Mecerli, Mickaël Bobot
Institutions: Université Toulouse - Jean Jaurès, Assistance Publique Hôpitaux de Marseille, Hôpital de la Conception, Inserm, Aix-Marseille Université, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Centre de Recherche en CardioVasculaire et Nutrition, Centre Européen de Recherche en Imagerie Médicale
Language: French
Subfield: Family Practice
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4415734600