Work

Evaluation of Antibiotic Resistance Patterns of Escherichia coli Isolated from Patients at a Hospital in Kerman city

Year: 2025

Type: article

Abstract: Background: Antibiotic resistance is a worldwide concern that decreases the beneficial effects of antibiotics. Escherichia coli is a prevalent etiological agent of infections, particularly within hospital intensive care units. Therefore, comprehending the antibiotic resistance profile of E. coli is essential for effective treatment. This study evaluated the antibiotic resistance characteristics of E. coli collected from patients admitted to Afzalipour hospital in Kerman, Iran. Methods: This retrospective study examined 139 patients hospitalized at Afzalipour hospital between September 2017 and August 2019. E. coli isolates from clinical specimens were evaluated for antibiotic susceptibility using disk diffusion and agar dilution techniques. The data were analyzed with a chi-square test in SPSS. Results: Cefazolin and cefotaxime were the most resistant drugs within the examined population. In contrast, gentamicin and amikacin demonstrated reduced resistance rates. The resistance level varied based on the sample type and the department where the patients were admitted. Conclusion: Excessive and wrong uses of antibiotics develop antibiotic resistance in E. coli. Therefore, gentamicin and amikacin can be considered to reduce antibiotic resistance challenges.

Source: Majallah-i dānishgāh-i ̒ulum-i pizishkī-i Kirmān.

DOI: 10.34172/jkmu.4103