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Study Report from the Pragmatic Assessment of the NuvoAir Clinical Service in the Management of Patients with Chronic Obstructive Pulmonary Disease

Year: 2025
Type: preprint
Abstract: Background COPD is one of the leading causes of death, disability and avoidable hospitalization in the US and abroad, yet proactive management of COPD has historically been limited. This study evaluates NuvoAir Home Service (NAHS), a novel intervention that integrates telemedicine, remote monitoring, and chronic-care management to deliver proactive care to patients with COPD. Methods We present findings from a six-month pragmatic program evaluation. Patients with COPD enrolled in NAHS were compared with propensity-matched controls using a two-period difference-in-difference (DID) design. Results 280 NAHS participants compared to 840 propensity matched controls showed a reduction of 47% in post-to-pre risk ratio (RR) for COPD-related hospitalization (p = 0.06), 55% in average days of hospital stay (p = 0.02), 53% in hospital readmissions (p = 0.32). There was no significant change in ED visits (p=0.83), and in outpatient office visits (p=0.89). All-cause utilization moved in similar directions, but none of those changes were statistically significant. COPD-related total medical cost and hospitalization cost from medical claims were also significantly reduced with a 28% reduction (p-value = 0.05) and a 53% reduction (p-value = 0.02) in post-to-pre cost ratio. No significant changes were observed in all-cause hospitalization, all-cause and COPD-related ED, outpatient, or pharmacy costs. Conclusion These data indicate that NuvoAir Home Service had a clinically positive impact on COPD-related hospital utilization and costs without significantly increasing ED or outpatient use, though not all results met statistical significance.
Source: medRxiv
DOI: 10.1101/2025.11.11.25339788
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W4416248306
Cites: 18
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Related to: 10