Age-Related Androgen Deficiency in the Urology Department of the Gabriel Touré University Hospital Centre
Year: 2025
Type: article
Study design: Observational Study
Abstract: To study age-related androgen deficiency (ARAD) in the urology department of Gabriel Touré University Hospital. Patients and Methods:This was a prospective descriptive study of cases of (ARAD) in the urology department of Gabriel TOURE Hospital in Bamako, Mali.The study was conducted over a period of one year, from 1 January 2020 to 31 December 2020.Results: During the study period, we received 1,951 patients for consultation at the urology department of the Gabriel Touré University Hospital, including 31 cases of ARAD, representing a frequency of 1.58%.The average age was 65 years.Married men were the most common, representing 77.4% of cases.Nearly half of the patients were businesspeople, representing 45.2% of cases.ARAD appeared gradually in 64.5% of patients.Nearly half of the patients had consulted for sexual asthenia (41.9%), followed by 35.5% for decreased libido.Most patients had sexual intercourse twice a week (45.2%)before the onset of the disorder.Nearly half of the patients had suffered from the disorder for several years (51.6% of cases).Most patients reported unchanged libido in 58.1% of cases.The majority of our patients were hypertensive in 38.7% of cases.Fasting blood glucose was normal in almost all non-diabetic patients, i.e. 48.39% of cases.Testosterone levels were decreased in 100% of cases.Prolactin levels were normal in more than 51.6% of patients.Serum FSH levels were normal in almost all patients, 74.2%.TSH levels were normal in the majority of patients, 71%.Nearly half of the patients had resorted to self-medication several months before their first consultation at the urology department, 58.1%.All our patients had undergone medical treatment.Most of our patients, 71%, showed progressive improvement in their health.In our series, androgen deficiency was observed in 67.7% of cases.According to the IIEF5 score, the following were normal in 38.7% of cases, mild in 22.6% of cases, slightly moderate in 12.9% of cases, and severe in 9.7% of cases.According to the AMS score, the following were normal in 32.3% of cases, mild in 32.3% of cases, moderate in 22.6% of cases, and severe in 12.9% of cases.Conclusion: ARAD seriously impairs clinical and biochemical signs and overall quality of life in older adults.Knowledge is incomplete and sometimes unclear, and some aspects of androgen replacement therapy remain controversial.
Source: Archives of Urology
Authors: Mamadou Tidiani Coulibaly, Moussa Salifou Diallo, Amadou Kassogué, Maimouna Traore
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4416307802