ANTIOXIDANT AND ANTl-INFLAMMATORY POTENTIAL OF AN EPIPHYTIC AND ENDANGERED ORCHID, DENDROBIUM MOSCHATUM (BUCH.-HAM.) SW
Year: 2021
Type: article
Abstract: Antioxidant and anti-inflammatory potential of Dendrobium moschatum fractions of root, stem, and leaf was investigated.The dried samples of these parts were extracted with Butanol-1, DCM (dichloromethane), n-Hexane, and Methanol fractions.Both Methanol fraction of root [IC 50 (inhibition concentration 50 µgml -1 ) = 30.21µgml -1 ] and leaf (IC 50 = 31.54µgml -1 ) possessed the most efficient antioxidant potential (free radical scavenging assay of DPPH) which was closely followed by DCM fraction of leaf with an IC 50 value of 33.78 µgml -1 .The least antioxidant activity (albumin denaturation technique) was seen in the n-Hexane fraction of leaf and IC 50 value was 94.74 µgml -1 .The lowest anti-inflammatory potential was shown by n-Hexane fraction of both root (IC 50 = 71.80µgml -1 ) and stem (IC 50 = 71.21µgml -1 ) while the highest anti-inflammation was demonstrated in root by Methanol fraction with an IC 50 value of 39.01µgml -1 closely followed in leaf by Butanol-1 fraction whose IC 50 value was 39.00 µgml -1 , n-hexane fraction (IC 50 = 39.21 µgml -1 ), and methanol fraction (IC 50 = 39.79 µgml -1 ).Hence, the results indicated that leaf part showed the most prospective anti-inflammatory activity.From the present study, it may be concluded that the plant has great medicinal potential and further researches are needed to explore its potential.
Source: J Orchid Soc India
Authors: Tsrii Sarqana, M M Hoque, M K Huda
Institution: University of Chittagong
Language: English
Subfield: Pharmacology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funder: University of Chittagong
OpenAlex ID: W4416356554