Year: 2025
Type: article
Study design: Case Report
Abstract: A healthy 12-year-old girl presented with asymptomatic skin lesions on the right cervical region, initially observed at 5 months of age.The lesions started on the neck and extended to the shoulder.Physical examination revealed multiple erythematous, shiny, 2-4 mm papulo-vesicles with occasional crust, converging into a large verrucous plaque (Fig. 1).Punch biopsy revealed dilated lymphatic vessels in the upper dermis (Fig. 2), confirming the diagnosis of lymphangioma circumscriptum (LC).Cutaneous lymphangiomas are lymphatic malformations with an estimated incidence of 2:1000 live births 1,2 .They are classified based on vessel depth and size 3 .The superficial group includes LC or microcystic lymphatic malformation; the deeper group includes cavernous lymphangiomas and cystic hygromas 3 .LC is the most common type and may be congenital or secondary to lymphatic abnormalities 4 .Somatic PIK3CA mutations may be present 4 .LC appears as translucent vesicles or flesh-colored papules, sometimes with violaceous discoloration 3,5 .Verrucous and hyperkeratotic changes are common 3 .Lesions typically affect the cervicofacial region and proximal limbs 4 .Histopathology shows dilated lymphatic vessels in the upper dermis, acanthosis, and hyperkeratosis 3,5 .Differential diagnoses include lymphangiectasias, hemangioma, angiokeratoma, and epidermal nevi 2,3 .Surgical excision is the treatment of choice, but
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416545239