Lithium and valproic acid in bipolar disorder: Beyond mood stabilization, the overlooked role of sleep
Year: 2025
Type: article
Abstract: examined sleep quality in bipolar disorder patients treated with lithium or valproic acid, showing lithium's advantage in habitual sleep efficiency and reduced disturbances. While this study provides valuable data in a chronic and clinically challenging cohort, reliance solely on self-reported sleep measures remains a limitation. Polysomnography, although the gold standard, is not always practical; therefore, actigraphy and wearable technologies represent feasible alternatives to capture objective sleep patterns. This letter emphasizes the importance of integrating objective, scalable technologies and pharmacological monitoring into longitudinal designs to clarify whether improvements in sleep translate into better clinical outcomes and reduced relapse risk in bipolar disorder.
Source: World Journal of Psychiatry
Author: Esra Kabadayi Sahin
Institution: Ankara Yıldırım Beyazıt University
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416617856