Work

Concordance of CTCs and cfDNA with Tissue Biopsy using See.d® and SBS Slides: A Feasibility Study in Metastatic Breast Cancer

Year: 2025

Type: article

Abstract: Introduction: In metastatic breast cancer (MBC), repeated assessment of tumor biology is essential to guide therapeutic decisions, yet tissue biopsies are invasive and difficult to repeat. Tumor-derived material, including Circulating Tumor Cells (CTCs) and cell-free DNA (cfDNA), provides a minimally invasive alternative. This study assessed the feasibility of a novel liquid biopsy workflow in MBC patients, using paired blood and metastatic tissue samples for biomarkers analysis.

Source: The Journal of Liquid Biopsy

DOI: 10.1016/j.jlb.2025.100394