Comparison of the Prevalence of Thrombocytopenia in Deceased and Recovered COVID-19 Patients Admitted to the ICU of Imam Khomeini Hospital, Ardabil
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Thrombocytopenia is a clinical manifestation of coronavirus disease 2019 , potentially leading to bleeding and affecting disease prognosis.This study aimed to compare the prevalence of thrombocytopenia in deceased and recovered COVID-19 patients admitted to the Intensive Care Unit (ICU) of Imam Khomeini Hospital, Ardabil.Methods: This cross-sectional study was conducted on 458 patients with confirmed COVID-19 admitted to the ICU of Imam Khomeini Hospital from April to September 2021.After applying exclusion criteria, 403 patients (136 recovered and 267 deceased) were analyzed.Demographic, clinical, and laboratory data, including thrombocytopenia severity, were extracted from medical records and analyzed using statistical tests (e.g., Chi-square and logistic regression).Results: Thrombocytopenia was observed in 18.4% (25 of 136 patients) of recovered patients and 76% (203 of 267 patients) of deceased patients.The mean age of patients with thrombocytopenia was significantly higher in the deceased group (70.27±13.62years) compared to the recovered group (61.20±15 years) (p=0.001).Heart failure was significantly associated with thrombocytopenia (p=0.038).Patients treated with remdesivir showed higher thrombocytopenia prevalence in the recovered (84%) and deceased (65.2%) groups, but this was not statistically significant.Conclusion: Older age and heart failure were associated with increased thrombocytopenia in deceased COVID-19 patients.Severe thrombocytopenia was linked to a higher mortality risk.
Source: مجله دانشگاه علوم پزشکی اردبیل
Institution: Ardabil University of Medical Sciences
Language: Persian
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4416631441