Work

Initial Experience of Multipurpose Mechanical Aspiration System for Acute High‐Risk Pulmonary Embolism: A Prospective Multi‐Center Case Series

Year: 2025

Type: article

Abstract: High-risk acute pulmonary embolism (PE) is associated with significant in-hospital mortality. Large-Bore Mechanical Thrombectomy (LBMT) is a treatment option for acute PE, but data on its efficacy in high-risk PE was limited. This prospective case series reported the outcomes of 14 patients with high-risk PE treated using a novel multipurpose mechanical aspiration system (MMAS). Most patients were in hemodynamic decompensation, requiring inotropic or mechanical circulatory support. The mean procedural time was 73.5 ± 39.2 min. Complete procedural success was achieved in 78.6% of the cases, while two patients required bailout therapies. The mean pulmonary arterial pressure decreased by 27.2%, and the right-ventricle/left-ventricle ratio normalized in 85.7% of patients. The primary endpoint-in-hospital mortality-was 0%, while the major bleeding rate was 27.2%. These findings suggest that MMAS is a safe and effective intervention for acute high-risk PE.

Source: Pulmonary Circulation

DOI: 10.1002/pul2.70206

Authors: GuangMing Tan, Timothy Ho Him Kam, Edbert Cheuk Yin Lai, Esmond Yan Hang Fong, Jake Yin Kei Yeung, Bryan Ping‐Yen Yan

Institutions: Chinese University of Hong Kong, Queen Elizabeth Hospital

Language: English

Topic: Venous Thromboembolism Diagnosis and Management

Subfield: Internal Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,310