Efficacy and safety of a mosaic HIV-1 vaccine regimen in men who have sex with men and transgender individuals (HVTN 706/HPX3002/Mosaico): a global, randomised, double-blind, placebo-controlled, phase 3 trial
Year: 2025
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Source: The Lancet HIV
Authors: Susan P Buchbinder, Sabrina Spinosa Guzman, Jorge Sanchez, Wouter Willems, Daniel J Stieh, Janine van Duijn, Mariska G M van Rosmalen, Jenny Hendriks, Steven Nijs, Ludo Lavreys, Carmen A Paez, Beatriz Grinzstejn, Julia Hutter, Philipp Mann, Juan G Sierra Madero, Pedro Cahn, Antonella Castagna, Carla Truyers, Sanne Roels, Peter B Gilbert, Marco Carone, Alex Luedtke, Lawrence Corey, Maria G Pau, Frank Tomaka, Susan Abdalian, Jorge Andrade Pinto, Michele Andrasik, Jessica Andriesen, Clovis Arns da Cunha, Maria Jesus Barbera, Gail Broder, Susan Buchbinder, Carlos Antonio Cabrera May, Pedro Cahn, Martin Wilfredo Casapia, Lidia Isabel Cassetti, Antonella Castagna, Giulio Corbelli, Gordon Crofoot, Jose Henrique da Silva Pilotto, Edwin De Jesus, Robert De La Grecca, Carlos Del Rio, Susanne Doblecki-Lewis, Katy Dougherty, Niles Eaton, Sri Edupuganti, Vicente Estrada, Irma L. Febo Rodriguez, Jorge Flores, Ian Frank, Mariel Franklin, Julie Franks, Jorge Gallardo Cartagena, Carmela Ganoza, Miguel Garcia Del Toro, Paul Goepfert, Rafael Gonzalez, Luz Alicia Gonzalez Hernandez, Miguel Gorgolas, Silvia Goulart, Alex Greninger, Beatriz Grinsztejn, Doug Grove, Jen Hanke, Jose Alfredo Hidalgo Vidal, John Hural, Megan Jones, Spyros Kalams, Esper Georges Kallas, Luciana Kamel, Andrzej Katafias, James G. Kublin, Marcus Lacerda, Javier Lama, Marcelo H. Losso, Sergio Lupo, José Valdez Madruga, Troy Martin, Kenneth Mayer, Valentina Mazzotta, Rachael McClennen, Julie McElrath, José Moltó-Marhuenda, Javier Morales-Ramirez, Cristina Mussini, Tamara Newman Lobato Souza, Richard Novak, Laurie Rinn, Antonio Rivero Román, Diego Sanchez Thomas, Patricia Segura, Juan Gerardo Sierra Madero, Magda Sobieszczyk, Carrie Sopher, Michael Stirewalt, Shobha Swaminathan, Bartosz Szetela, Hong Van Tieu, India Tindale, Javier Valencia, Stephaun Elite Wallace, Stephen Walsh, Haven Wilvich
Institutions: San Francisco Department of Public Health, Johnson & Johnson (Netherlands), National University of San Marcos, Fred Hutch Cancer Center, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, National Institute of Allergy and Infectious Diseases, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Fundación Huésped, Vita-Salute San Raffaele University, University of Washington, Johnson & Johnson (United States)
Language: English
Topic: HIV Research and Treatment
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
Awards: G6928345451, HIV Vaccine Trials Network Laboratory Center, University of Pennsylvania HIV Clinical Trials Unit, HIV Vaccines Clinical Trials Network Leadership and Operations Center, SDMC: HIV Vaccine Trials Network, ICAP Clinical Trials Unit, PERU Clinical Trial Unit, Penn Center for AIDS Research, San Francisco Bay Clinical Trials Unit (CTU), Seattle Clinical Trials Unit
OpenAlex ID: W4416713344